6-Chloro-7-((4-(trifluoromethoxy)phenyl)amino)isoquinoline-5,8-dione CAS 296776-08-4
| CAS No. | 296776-08-4 |
| Molecular Formula | C16H8ClF3N2O3 |
| Molecular Weight | 368.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H8ClF3N2O3, 6-Chloro-7-((4-(trifluoromethoxy)phenyl)amino)isoquinoline-5,8-dione contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 368.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Chloro-7-((4-(trifluoromethoxy)phenyl)amino)isoquinoline-5,8-dione (CAS 296776-08-4), molecular formula C16H8ClF3N2O3 and molecular weight 368.69 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-7-((4-(trifluoromethoxy)phenyl)amino)isoquinoline-5,8-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8ClF3N2O3 |
| Molecular Weight | 368.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 7-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one (CAS 882747-40-2)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-6-nitroquinazolin-4-amine (CAS 1290545-23-1)
- 1-[4-chloro-3-(trifluoromethyl)phenyl]-5-pyridin-4-yl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1326937-41-0)
- 1-[2-chloro-5-(trifluoromethyl)phenyl]-5-pyridin-4-yl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351779-28-6)
- 3-Chloro-5-(difluoro-pentafluorophenyl-methylsulfanyl)-[1,2,4]thiadiazole 3-chloro-5-(perfluorobenzylthio)-1,2,4-thiadiazole 36955-45-0 A6365 (CAS 36955-45-0)
- 1-Benzyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl trifluoromethanesulfonate (CAS 856250-49-2)
- 2-[(E)-2-[(2-Chloro-6-fluorophenyl)methylidene]hydrazin-1-yl]-3-(trifluoromethyl)quinoxaline (CAS 338962-29-1)
- Ethyl 2-((2-chloro-4-fluorophenyl)imino)-4-(trifluoromethyl)-2,3-dihydrothiazole-5-carboxylate (CAS 937597-86-9)
Recommended Standards
- 1H-Isochromene-1,3,4-trione 4-{N-[4-chloro-3-(trifluoromethyl)phenyl]hydrazone} (CAS 339100-72-0)
- 5-Chloropyridin-3-yl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 1041426-05-4)
- N1,N4-Didecylbutane-1,4-diamine (CAS 41596-82-1)
- N1-(2-chloroethanimidoyl)-3,5-di(trifluoromethyl)benzene-1-sulphonamide (CAS 680579-96-8)
- 3-(t-Butoxycarbonylamino)-2-chloropyridine-5-boronic acid (CAS 2096329-87-0)
- Methyl 6-bromo-5-chloropyrazine-2-carboxylate (CAS 1017603-87-0)
- N-((1-methyl-1H-imidazol-2-yl)methyl)thietan-3-amine (CAS 1856444-18-2)
- 5-Acetyl-6-methyl-2-(((3-phenylisoxazol-5-yl)methyl)amino)nicotinonitrile (CAS 338749-67-0)
- 3-(3,4-Dimethoxyphenyl)-1-methyl-4,5,6,7-tetrahydro-1H-indazol-4-one (CAS 41555-68-4)
- 2-Chloro-N-(1-methylpiperidin-4-yl)pyrimidin-4-amine (CAS 954229-26-6)
- 2-(1-Hydroxycyclobutyl)butanoic acid (CAS 1248825-43-5)
- 6-Bromo-2,3-difluorothioanisole (CAS 1394291-28-1)
- 2-(Cbz-amino)propanamide (CAS 2503-29-9)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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