7-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one CAS 882747-40-2

Purity 97%+In StockPharmaceutical Standards
CAS No.882747-40-2
Molecular FormulaC16H8ClF3N2O3
Molecular Weight368.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one CAS 882747-40-2 chemical structure

Description

The occurrence of 7-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 7-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one (CAS 882747-40-2), a certified reference material (molecular formula C16H8ClF3N2O3, MW 368.69 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 7-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 368.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H8ClF3N2O3
Molecular Weight368.69 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing
Nitrogen Atoms2

Related Chloro Standards

Recommended Standards

Why CATO?