5-(4-((4-Fluorobenzyl)oxy)phenyl)-N-(4-fluorophenyl)thiazol-2-amine CAS 297150-36-8
| CAS No. | 297150-36-8 |
| Molecular Formula | C22H16F2N2OS |
| Molecular Weight | 394.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-((4-Fluorobenzyl)oxy)phenyl)-N-(4-fluorophenyl)thiazol-2-amine (CAS 297150-36-8) is a high-purity analytical reference standard with the molecular formula C22H16F2N2OS and a molecular weight of 394.44 g/mol.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 5-(4-((4-Fluorobenzyl)oxy)phenyl)-N-(4-fluorophenyl)thiazol-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 394.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4-((4-Fluorobenzyl)oxy)phenyl)-N-(4-fluorophenyl)thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16F2N2OS |
| Molecular Weight | 394.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- 2-((5-((4-Fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-1-(4-fluorophenyl)ethanone (CAS 477330-25-9)
- 2-((4-Fluorobenzyl)thio)-5-(thieno[2,3-b]quinolin-2-yl)-1,3,4-oxadiazole (CAS 692737-18-1)
- (4-(4-Fluorobenzyl)-4-hydroxypiperidin-1-yl)(2-(pyrimidin-4-yl)pyridin-3-yl)methanone (CAS 1429505-54-3)
- 4-(4-Fluorobenzyl)-3-((3-methoxybenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 294853-33-1)
- 2-[4-(4-Fluorobenzyl)-1-piperidinyl]-2-oxo-N-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide (CAS 496054-87-6)
- 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(pyridin-4-yl)pyrimidin-4-amine (CAS 402595-29-3)
- (4-((4-Fluorobenzyl)oxy)-1-(4-fluorophenyl)-1H-pyrazol-3-yl)(piperidin-1-yl)methanone (CAS 1185099-03-9)
- 5-(2-Fluorobenzyl)-3-(4-methoxyphenyl)-8-methyl-5H-pyrazolo[4,3-c]quinoline (CAS 866809-58-7)
Recommended Standards
- 4-Methyl-N-(7-methyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepin-2-yl)benzenesulfonamide (CAS 866152-15-0)
- 5-(8-Ethoxy-2-oxo-2H-chromen-3-yl)-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-3-one (CAS 313985-92-1)
- 3-((4-Hydroxyphenyl)(4-methoxybenzyl)amino)benzo[d]isothiazole 1,1-dioxide (CAS 433254-23-0)
- 6-Benzyl 2-(tert-butyl) (S)-8-fluoro-8-(hydroxymethyl)-2,6-diazaspiro[3.4]Octane-2,6-dicarboxylate (CAS 2052992-88-6)
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- 5-Bromo-2,2-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine (CAS 1637490-65-3)
- (2R)-1-Methoxypent-4-yn-2-ol (CAS 2089246-31-9)
- 1-((2R,3R,4S,5S)-3-Hydroxy-5-(hydroxymethyl)-4-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 444020-64-8)
- 2,6-diethylmorpholine (CAS 52382-34-0)
- 3-Hydroxy-2-nitrobenzenesulfonyl chloride (CAS 1261554-31-7)
- 6-Bromo-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 2377606-25-0)
- (R)-7-Chloro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (CAS 1257526-91-2)
- 2-3-O-Isopropylidene-L-gulonic acid-1-4-lactone (CAS 94840-08-1)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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