3-Hydroxy-N-((6S,9S,12S,15R,16S,19R,23R,24aR)-23-hydroxy-19-isobutyl-2,5,9,11,15-pentamethyl-6-((S)-3-methylbutan-2-yl)-1,4,7,10,13,17,20-heptaoxo-12-phenyldocosahydro-1H-pyrrolo[2,1-o][1,4,7,10,13,16,19]oxahexaazacyclodocosin-16-yl)picolinamide CAS 299-20-7

Purity 97%+In StockPharmaceutical Standards
CAS No.299-20-7
Molecular FormulaC44H62N8O11
Molecular Weight879.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Hydroxy-N-((6S,9S,12S,15R,16S,19R,23R,24aR)-23-hydroxy-19-isobutyl-2,5,9,11,15-pentamethyl-6-((S)-3-methylbutan-2-yl)-1,4,7,10,13,17,20-heptaoxo-12-phenyldocosahydro-1H-pyrrolo[2,1-o][1,4,7,10,13,16,19]oxahexaazacyclodocosin-16-yl)picolinamide CAS 299-20-7 chemical structure

Description

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

3-Hydroxy-N-((6S,9S,12S,15R,16S,19R,23R,24aR)-23-hydroxy-19-isobutyl-2,5,9,11,15-pentamethyl-6-((S)-3-methylbutan-2-yl)-1,4,7,10,13,17,20-heptaoxo-12-phenyldocosahydro-1H-pyrrolo[2,1-o][1,4,7,10,13,16,19]oxahexaazacyclodocosin-16-yl)picolinamide (CAS 299-20-7), molecular formula C44H62N8O11 and molecular weight 879.01 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-Hydroxy-N-((6S,9S,12S,15R,16S,19R,23R,24aR)-23-hydroxy-19-isobutyl-2,5,9,11,15-pentamethyl-6-((S)-3-methylbutan-2-yl)-1,4,7,10,13,17,20-heptaoxo-12-phenyldocosahydro-1H-pyrrolo[2,1-o][1,4,7,10,13,16,19]oxahexaazacyclodocosin-16-yl)picolinamide (C44H62N8O11) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC44H62N8O11
Molecular Weight879.01 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)18.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms8

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