4-Fluoro-3-(morpholine-4-sulfonyl)benzoic acid CAS 299181-56-9
| CAS No. | 299181-56-9 |
| Molecular Formula | C11H12FNO5S |
| Molecular Weight | 289.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Fluoro-3-(morpholine-4-sulfonyl)benzoic acid (CAS 299181-56-9) is a high-purity analytical reference standard with the molecular formula C11H12FNO5S and a molecular weight of 289.28 g/mol.
The molecular framework of 4-Fluoro-3-(morpholine-4-sulfonyl)benzoic acid (C11H12FNO5S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12FNO5S |
| Molecular Weight | 289.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-HYDROXY-5-PHENYL-2-(PHENYLETHYNYL)-6H-1,3-OXAZIN-6-ONE (CAS 881877-45-8)
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- 2-[2-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid (CAS 1157562-08-7)
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- 2-Amino-N-(3-bromophenyl)benzamide (CAS 22312-63-6)
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- 5-Chloro-3-((4-chlorophenyl)sulfonyl)-2-methyl-1H-indole-6-carbonitrile (CAS 646514-54-7)
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- 3-((4-Chlorophenyl)thio)-1-(naphthalen-2-yl)propan-1-one (CAS 882073-33-8)
- 4-(Pyridin-4-yloxy)benzoic acid hydrochloride (CAS 1306606-31-4)
- Glucagon (1-29) (CAS 16941-32-5)
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