4-[4-(4-bromophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol CAS 299952-16-2
| CAS No. | 299952-16-2 |
| Molecular Formula | C16H9BrF3NO3 |
| Molecular Weight | 400.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[4-(4-bromophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-[4-(4-bromophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol (CAS 299952-16-2), a certified reference material (molecular formula C16H9BrF3NO3, MW 400.15 g/mol) for analytical method development and quality control.
The molecular framework of 4-[4-(4-bromophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol (C16H9BrF3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[4-(4-bromophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H9BrF3NO3 |
| Molecular Weight | 400.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related bromophenyl Standards
- 2-(4-Bromophenyl)-5-(pentafluoro-λ6-sulfanyl)benzo[d]oxazole (CAS 1379811-79-6)
- 2-(2-Bromophenyl)-5-(pentafluoro-λ6-sulfanyl)benzo[d]oxazole (CAS 1379811-82-1)
- 2-(3-Bromophenyl)-5-(pentafluoro-λ6-sulfanyl)benzo[d]oxazole (CAS 1379812-03-9)
- 1-(4-Bromophenyl)-3-((4-bromophenyl)thio)propan-1-one (CAS 882749-13-5)
- 2-(4-Bromophenyl)-3-(2-carboxyethyl)quinoline-4-carboxylic acid (CAS 1263215-96-8)
- 5-(2-Bromophenyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol (CAS 702646-09-1)
- 4-((1-((2-Bromophenyl)sulfonyl)azetidin-3-yl)oxy)-6-methyl-2H-pyran-2-one (CAS 1795446-84-2)
- (2E)-3-(4-Bromophenyl)-2-[2-(3,5-dichlorophenyl)hydrazin-1-ylidene]-3-oxopropanal (CAS 338414-05-4)
Recommended Standards
- 4,4'-Diselanediyldibenzoic acid (CAS 36297-88-8)
- 5-(4-Methyl-2-nitrophenyl)pent-4-yn-1-ol (CAS 915402-23-2)
- 2,2'-Diselanediyldibenzoic acid (CAS 6512-83-0)
- Brivaracetam Impurity 137 (CAS CATO-C4X-2007137)
- Iberdomide (CC220) (CAS 1323403-33-3)
- (4-(Difluoromethyl)-3-nitro-6-(trifluoromethoxy)pyridin-2-yl)methanol (CAS 1805292-20-9)
- 2-((3-Mercaptopropyl)thio)-1-(1H-pyrrol-2-yl)ethanone (CAS 929004-82-0)
- [(3S)-3-fluorooxolan-3-yl]methanol (CAS 1268492-92-7)
- 4-((3-Chlorophenyl)sulfonamido)benzoic acid (CAS 727689-55-6)
- Fmoc-L-Sec(phenyl)-OH (CAS 312746-41-1)
- Ethyl 3-Amino-5-chloro-4-(1-piperidinyl)benzoate (CAS 1315374-29-8)
- 4-(Difluoromethyl)-2-iodo-3-nitro-5-(trifluoromethoxy)pyridine (CAS 1804360-40-4)
- 2,2,4,6,6-Pentamethylheptane (CAS 13475-82-6)
- Peptide 435 (CAS CATO-CPTD788435)
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