Brivaracetam Impurity 137 CAS CATO-C4X-2007137
| CAS No. | CATO-C4X-2007137 |
| Molecular Formula | C14H24Br2O3 |
| Molecular Weight | 400.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Brivaracetam Impurity 137 (CAS CATO-C4X-2007137, C14H24Br2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, Brivaracetam Impurity 137 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 400.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H24Br2O3 |
| Molecular Weight | 400.15 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Br-containing |
Related Brivaracetam Standards
- Brivaracetam Impurity 142 (CAS CATO-C4X-2007142)
- Brivaracetam Impurity 150 (CAS CATO-C4X-2007150)
- Brivaracetam Impurity 132 (CAS CATO-C4X-2007132)
- Brivaracetam Impurity 44 (CAS CATO-C4X-200744)
- Brivaracetam Impurity 126 (CAS CATO-C4X-2007126)
- Brivaracetam Impurity 118 (CAS CATO-C4X-2007118)
- Brivaracetam Impurity 45 (CAS CATO-C4X-200745)
- Brivaracetam Impurity 128 (CAS CATO-C4X-2007128)
Recommended Standards
- 5-(4-Methyl-2-nitrophenyl)pent-4-yn-1-ol (CAS 915402-23-2)
- 2-Fluoro-5-methyl-3-(tributylstannyl)pyridine (CAS 1025745-87-2)
- 4-[4-(4-bromophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol (CAS 299952-16-2)
- 2-(4-Bromophenyl)-5-(pentafluoro-λ6-sulfanyl)benzo[d]oxazole (CAS 1379811-79-6)
- Ivabradine impurity 69 (CAS CATO-C4X-111969)
- Dapagliflozin impurity 215 (CAS CATO-C4X-1138215)
- Ixazomib Impurity 46 (CAS CATO-C4X-126746)
- 2-(3,4-Dihydro-2h-1-benzopyran-6-yl)ethan-1-ol (CAS 145760-40-3)
- 2-(Cyclopropylamino)-6-methylpyrimidin-4-ol (CAS 5734-72-5)
- 2-(Aminomethyl)benzamide (CAS 63056-17-7)
- 3-Cyclopropoxy-N-methyl-5-nitropyridin-2-amine (CAS 1243479-94-8)
- 1-(4-Fluorophenyl)-3-(thiazol-2-yl)thiourea (CAS 457-82-9)
- 2-((6-Thioxo-1,6-dihydropyridazin-3-yl)oxy)ethyl acetate (CAS 89225-75-2)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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