Ethyl 5-(4-chlorophenyl)-2-(3,4-dimethoxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate CAS 300377-46-2
| CAS No. | 300377-46-2 |
| Molecular Formula | C25H23ClN2O5S |
| Molecular Weight | 498.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C25H23ClN2O5S, Ethyl 5-(4-chlorophenyl)-2-(3,4-dimethoxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 498.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Ethyl 5-(4-chlorophenyl)-2-(3,4-dimethoxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 300377-46-2), a certified reference material (molecular formula C25H23ClN2O5S, MW 498.98 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 5-(4-chlorophenyl)-2-(3,4-dimethoxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H23ClN2O5S |
| Molecular Weight | 498.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
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- 4-{[(4-chlorophenyl)methyl]sulfanyl}-6-[(4-fluorophenyl)sulfanyl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene (CAS 478065-78-0)
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- 2-((4-(4-Chlorophenyl)-3-cyano-6-(4-methoxyphenyl)pyridin-2-yl)thio)-N-phenylpropanamide (CAS 444157-50-0)
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Recommended Standards
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- 7-AVCA Impurity 4 (CAS CATO-C4X-23164)
- 1-(Pentan-2-yl)-1H-pyrazol-4-amine (CAS 1240567-88-7)
- 2-(2-Bromophenyl)-N-methoxy-N-methylacetamide (CAS 177756-64-8)
- But-3-en-1-yl methanesulfonate (CAS 40671-34-9)
- 1-(Thien-2-ylcarbonyl)piperidin-3-aminehydrochloride (CAS 1114596-44-9)
- 2-(3-Aminophenoxy)aniline (CAS 99739-88-5)
- 4-Fluoro-3-hydrazineylphenol (CAS 1314929-35-5)
- Tert-butyl 3-(4-chlorophenyl)-3-(trifluoromethyl)piperazine-1-carboxylate (CAS 1639963-99-7)
- 3-[(E)-1-Nitro-2-(phenylamino)ethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 338753-92-7)
- 6-(tert-Butyl)-2-chloropyrimidine-4-carbonitrile (CAS 2091036-80-3)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
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