4-(tert-Butoxy)phenol CAS 301353-98-0
| CAS No. | 301353-98-0 |
| Molecular Formula | C22H20Br2N2O2 |
| Molecular Weight | 504.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(tert-Butoxy)phenol.
4-(tert-Butoxy)phenol (CAS 301353-98-0) is a high-purity analytical reference standard with the molecular formula C22H20Br2N2O2 and a molecular weight of 504.21 g/mol.
4-(tert-Butoxy)phenol (C22H20Br2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(tert-Butoxy)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20Br2N2O2 |
| Molecular Weight | 504.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related tert Standards
- 5-((3-(4-Butoxy-3-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(sec-butyl)-2-thioxothiazolidin-4-one (CAS 624724-33-0)
- (3-(Tert-butoxy)-2',6'-diisopropyl-[1,1'-biphenyl]-2-yl)dicyclohexylphosphane (CAS 2489243-27-6)
- 4-(4-Butoxy-3-methylbenzoyl)-1-(2-(dimethylamino)ethyl)-5-(4-ethoxy-3-methoxyphenyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 487039-63-4)
- 6-Butoxy-2,4-diiodo-3H-xanthen-3-one (CAS 161728-47-8)
- 4-Butoxy-N-((3-(5,6-dimethylbenzo[d]oxazol-2-yl)-2-methylphenyl)carbamothioyl)benzamide (CAS 590397-26-5)
- 5-(4-Butoxy-3-ethoxyphenyl)-3-hydroxy-4-(7-methoxybenzofuran-2-carbonyl)-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 7051-20-9)
- 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid (CAS 1803609-23-5)
- 5-(4-Butoxy-3-ethoxybenzylidene)-2-(3-methylbenzofuran-2-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 618078-22-1)
Recommended Standards
- (S)-1-(3,6-Dibromo-9H-carbazol-9-yl)-3-((3-methoxyphenyl)amino)propan-2-ol (CAS 1235481-43-2)
- P7C3‐OMe, 97% (CAS 313268-18-7)
- (R)-1-(3,6-Dibromo-9H-carbazol-9-yl)-3-((3-methoxyphenyl)amino)propan-2-ol (CAS 1235481-41-0)
- (R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione 1035555-63-5 C17H16FIN4O4 X7440 (CAS 1035555-63-5)
- 5-bromo-4-chloro-6-methylthieno[2,3-d]pyrimidine (CAS 1388892-94-1)
- 1-(4-((2-Aminoethyl)(methyl)amino)piperidin-1-yl)ethanone (CAS 1353974-60-3)
- 1-(4-((4-Ethoxynaphthalen-1-yl)sulfonyl)piperazin-1-yl)ethan-1-one (CAS 941008-51-1)
- rac-(2R,3R)-4-methyl-3-(1-methyl-1H-pyrazol-4-yl)-5-oxomorpholine-2-carboxylic acid (CAS 1909286-93-6)
- 7-Ethoxy-4-methylquinolin-2(1H)-one (CAS 105908-28-9)
- Methyl N-(methylsulfonyl)-N-phenylglycinate (CAS 412939-60-7)
- 5-Amino-2-methyl-4H-pyrrolo[1,2-b]pyrazol-6(5H)-one (CAS 802323-69-9)
- 2-Chloro-6-(N,N-dipropylamino)pyrazine (CAS 957065-91-7)
- (3,5-Dichlorophenyl)(3,5-difluorophenyl)methanone (CAS 844885-17-2)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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