5-(4-Butoxy-3-ethoxybenzylidene)-2-(3-methylbenzofuran-2-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 618078-22-1
| CAS No. | 618078-22-1 |
| Molecular Formula | C26H25N3O4S |
| Molecular Weight | 475.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(4-Butoxy-3-ethoxybenzylidene)-2-(3-methylbenzofuran-2-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(4-Butoxy-3-ethoxybenzylidene)-2-(3-methylbenzofuran-2-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 618078-22-1), molecular formula C26H25N3O4S and molecular weight 475.56 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(4-Butoxy-3-ethoxybenzylidene)-2-(3-methylbenzofuran-2-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (C26H25N3O4S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 475.56 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25N3O4S |
| Molecular Weight | 475.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Butoxy Standards
- 4-Butoxy-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)benzamide (CAS 651054-48-7)
- 5-tert-Butoxy-5-oxo-2-(4,5,6,7-tetrachloro-1,3-dioxo-isoindolin-2-yl)pentanoic acid (CAS 2227107-17-5)
- 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopentane-1-carboxylic acid (CAS 1803609-23-5)
- (3-((4-(tert-Butoxy)phenoxy)methyl)-3,4-dihydroisoquinolin-2(1H)-yl)(naphthalen-1-yl)methanone (CAS 1380548-02-6)
- 4-Butoxy-N-((3-(5,6-dimethylbenzo[d]oxazol-2-yl)-2-methylphenyl)carbamothioyl)benzamide (CAS 590397-26-5)
- 3-{[(tert-butoxy)carbonyl]amino}-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-3-carboxylic acid (CAS 1589084-56-9)
- 4-(tert-Butoxy)phenol (CAS 301353-98-0)
- 4-Butoxy-N-(2-((4-(pyridin-2-yl)piperazin-1-yl)sulfonyl)ethyl)benzamide (CAS 946200-93-7)
Recommended Standards
- 2-(2-Methoxyphenyl)-N-(2-morpholino-5-(morpholinosulfonyl)phenyl)acetamide (CAS 849121-82-0)
- Dimethyl 5-((2-cyano-2-(4-(4-isobutylphenyl)thiazol-2-yl)vinyl)amino)isophthalate (CAS 796881-63-5)
- 2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 477330-65-7)
- Methyl 3-(6-methoxy-1-(p-tolyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-2-carboxamido)thiophene-2-carboxylate (CAS 931941-76-3)
- 5-Amino-2-fluorobenzonitrile hydrochloride (CAS 801316-08-5)
- Dermorphin Trifluoroacetic Acid Salt (CAS 78331-26-7)
- 1-(2-Amino-4-fluorophenyl)-2,2,2-trifluoroethanol (CAS 1785345-23-4)
- Tetrahydrothiophen-3-ol (CAS 3334-05-2)
- (2-Ethyl-1,3-thiazol-4-yl)methanol hydrochloride (CAS 1609395-65-4)
- 4-[(E)-2-(4-Chlorophenyl)ethenyl]-8-phenoxy-2H,3H-thieno[3,2-c]quinoline (CAS 865658-54-4)
- 2,2'-(Hexane-1,6-diylbis(sulfanediyl))bis(N-(4-chlorophenyl)acetamide) (CAS 882083-22-9)
- 2-(2-(2-(2-(Methylamino)-5-nitrophenoxy)ethoxy)ethoxy)ethanol (CAS 194923-89-2)
- (R)-4-((tert-Butyldiphenylsilyl)oxy)dihydrofuran-3(2H)-one (CAS 2641062-43-1)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com