N-(3-((3-Hydroxyphenyl)amino)quinoxalin-2-yl)benzenesulfonamide CAS 301357-74-4
| CAS No. | 301357-74-4 |
| Molecular Formula | C20H16N4O3S |
| Molecular Weight | 392.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-((3-Hydroxyphenyl)amino)quinoxalin-2-yl)benzenesulfonamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3-((3-Hydroxyphenyl)amino)quinoxalin-2-yl)benzenesulfonamide (CAS 301357-74-4), molecular formula C20H16N4O3S and molecular weight 392.43 g/mol, is a CATO reference standard with documented purity and traceability.
N-(3-((3-Hydroxyphenyl)amino)quinoxalin-2-yl)benzenesulfonamide (C20H16N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16N4O3S |
| Molecular Weight | 392.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- N-(2-(tert-Butyl)-5,5-dioxido-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-2-methyl-3-nitrobenzamide (CAS 449784-33-2)
- N-(3-Methoxyphenyl)-2-((3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetamide (CAS 868969-79-3)
- Dovitinib (CAS 405169-16-6)
- 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 (CAS 804551-71-1)
- 4-(Difluoromethyl)-2-hydrazinyl-6-(3-methoxyphenyl)pyrimidine (CAS 861226-63-3)
- (4-(Pyrrolidin-1-yl)pyridin-2-yl)methanamine (CAS 1248922-05-5)
- 3,5-Dichloro-4-methylbenzaldehyde (CAS 1350363-72-2)
- Phytonadione Impurity 8 (CAS 2241755-02-0)
- H-Met-Tyr-Lys-OH (H-4375.0050) (CAS 73674-95-0)
- 4-(4-Fluorophenoxy)-1H-pyrazole (CAS 1429902-97-5)
- 2-(3-Hydroxypyrrolidin-1-yl)isonicotinonitrile (CAS 1261234-97-2)
- 6,8-Difluorochroman-4-amine (CAS 886762-80-7)
- 4-(Tert-butyl)cycloheptane-1-sulfonamide (CAS 1492776-64-3)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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