4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 CAS 804551-71-1
| CAS No. | 804551-71-1 |
| Molecular Formula | C21H21FN6O |
| Molecular Weight | 392.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 (CAS 804551-71-1), a certified reference material (molecular formula C21H21FN6O, MW 392.43 g/mol) for analytical method development and quality control.
4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 (C21H21FN6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21FN6O |
| Molecular Weight | 392.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Amino Standards
- (E)-4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)quinolin-2(3H)-one (CAS 1027263-12-2)
- 3-Amino-7-methyl-N-(2-methyl-4-nitrophenyl)thieno[2,3-b]quinoline-2-carboxamide (CAS 332885-30-0)
- 3-Amino-N-(4-fluorophenethyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-19-3)
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- 2-(Cis-4-amino-3-oxoisoxazolidin-5-yl)acetic acid (CAS 2644-50-0)
- 5-Amino-1-(4-bromobenzyl)-N-(thiophen-2-ylmethyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899736-74-4)
- 2-Amino-4-(3-iodophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 296798-10-2)
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Recommended Standards
- N-(3-Methoxyphenyl)-2-((3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetamide (CAS 868969-79-3)
- Vardenafil EP Impurity B (CAS 437717-43-6)
- N-(3-((3-Hydroxyphenyl)amino)quinoxalin-2-yl)benzenesulfonamide (CAS 301357-74-4)
- Valsartan Impurity 126 (CAS CATO-C4X-1057126)
- 4,4-Dimethyl-2-(pyridin-2-yl)-4,5-dihydrooxazole (CAS 109660-12-0)
- 2-(3-Methoxybenzyl)-3-(p-tolyl)-2H-indazole (CAS 872682-11-6)
- Ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate (CAS 672323-07-8)
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- 5-Bromoquinazolin-4-amine (CAS 1201784-87-3)
- tert-Butyl 6-methylbenzofuran-2-carboxylate (CAS 1210226-83-7)
- Oxetan-3-yl(phenyl)methanamine (CAS 2383987-27-5)
- Peptide 442 (CAS CATO-CPTD788442)
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