Cefazolin EP Impurity A CAS 30246-33-4
| CAS No. | 30246-33-4 |
| Molecular Formula | C11H12N4O3S3 |
| Molecular Weight | 344.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Cefazolin EP Impurity A (CAS 30246-33-4, C11H12N4O3S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cefazolin EP Impurity A (C11H12N4O3S3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Cefazolin EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12N4O3S3 |
| Molecular Weight | 344.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 3 |
Related Cefazolin Standards
- Cefazolin Impurity 36 (CAS CATO-C4X-157736)
- Cefazolin 3-Hydroxymethyl Impurity Sodium Salt (CAS 50971-65-8)
- Cefazolin Impurity 11 (CAS 478494-71-2)
- Cefazolin EP Impurity J (CAS 1675245-00-7)
- Cefazolin USP Related Compound D(Diastereoisomer Mixture) (CAS 1675245-01-8)
- Cefazolin Impurity 89 (CAS CATO-C4X-157789)
- Cefazolin Impurity 70 (CAS CATO-C4X-157770)
- Cefazolin Impurity 85 (CAS CATO-C4X-157785)
Recommended Standards
- Mianserin EP Impurity B (CAS CATO-C4X-13698)
- Mianserin Hydrochloride EP Impurity B (CAS CATO-C4X-136930)
- Tiapride EP Impurity D (CAS 63484-11-7)
- Olanzapine Impurity 8 (CAS 1320360-87-9)
- Telmisartan impurity 74 (CAS CATO-C4X-135974)
- Fasudil impurity 32 (CAS CATO-C4X-136561)
- Atorvastatin Impurity N2 (CAS 40281-50-3)
- methyl 4-chloro-1H-pyrazolo[4,3-c]pyridine-3-carboxylate (CAS 1658466-48-8)
- 2-cyano-3-(2,6-dichlorophenyl)acrylamide (CAS 338792-83-9)
- 5-(2-Phenyl-1H-indol-3-yl)pyridazine-4-carbonitrile (CAS 919785-69-6)
- 1-Methoxy-N-(3-methylphenethyl)propan-2-amine (CAS 1249343-39-2)
- 3,5-Diiodo-2-methylpyridin-4-amine (CAS 1227266-99-0)
- 2-(Hex-1-yn-1-yl)benzaldehyde (CAS 106824-45-7)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com