Favipiravir Impurity 22 HCl CAS 30250-67-0
| CAS No. | 30250-67-0 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Favipiravir Impurity 22 HCl.
As a process- or degradation-related impurity, Favipiravir Impurity 22 HCl (CAS 30250-67-0, C10H10N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H10N2O2HCl, Favipiravir Impurity 22 HCl contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Favipiravir Impurity 22 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 HCl |
| Molecular Weight | 226.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Favipiravir Standards
- Favipiravir Impurity 16 (CAS 1023813-21-9)
- Favipiravir Impurity 9 (CAS 1079990-21-8)
- Favipiravir Impurity 17 (CAS 1137606-76-8)
- Favipiravir Impurity 21 (CAS 1207609-52-6)
- Favipiravir Impurity 32 (CAS 1207614-48-9)
- Favipiravir Impurity 19 (CAS 1257072-34-6)
- Favipiravir Impurity 6 (CAS 1374986-27-2)
- Favipiravir Impurity 23 (CAS 2091074-00-7)
Recommended Standards
- Avanafil Impurity 158 (CAS CATO-C4X-1118158)
- Loperamide EP Impurity G (CAS CATO-C4X-178810)
- Crisaborole impurity 127 (CAS CATO-C4X-2021127)
- Methyl (2-(hydroxymethyl)phenyl)carbamate (CAS 117550-36-4)
- 2-Ethyl-3-piperidinone Hydrochloride (CAS 1159826-57-9)
- (R)-1-(Thiazol-4-yl)ethanamine (CAS 1344412-36-7)
- Sodium Valproate Impurity 14 (CAS 1636-27-7)
- (1E)-N-(4-{[(4-fluorophenyl)methyl]sulfanyl}phenyl)-1-(thiophen-2-yl)methanimine (CAS 882083-97-8)
- Diethyl 2,3-diphenylsuccinate (CAS 3059-23-2)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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