3-(4-Bromobenzyl)-7-chloroquinazolin-4(3H)-one CAS 302913-21-9

Purity 97%+In StockPharmaceutical Standards
CAS No.302913-21-9
Molecular FormulaC15H10BrClN2O
Molecular Weight349.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Bromobenzyl)-7-chloroquinazolin-4(3H)-one CAS 302913-21-9 chemical structure

Description

The occurrence of 3-(4-Bromobenzyl)-7-chloroquinazolin-4(3H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-(4-Bromobenzyl)-7-chloroquinazolin-4(3H)-one (CAS 302913-21-9), molecular formula C15H10BrClN2O and molecular weight 349.61 g/mol, is a CATO reference standard with documented purity and traceability.

3-(4-Bromobenzyl)-7-chloroquinazolin-4(3H)-one (C15H10BrClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(4-Bromobenzyl)-7-chloroquinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H10BrClN2O
Molecular Weight349.61 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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