7-Chloro-3-(2-fluorobenzyl)quinazolin-4(3H)-one CAS 302913-39-9
| CAS No. | 302913-39-9 |
| Molecular Formula | C15H10ClFN2O |
| Molecular Weight | 288.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-Chloro-3-(2-fluorobenzyl)quinazolin-4(3H)-one (C15H10ClFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
7-Chloro-3-(2-fluorobenzyl)quinazolin-4(3H)-one (CAS 302913-39-9), molecular formula C15H10ClFN2O and molecular weight 288.70 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-3-(2-fluorobenzyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFN2O |
| Molecular Weight | 288.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 6-Chloro-3-(2-fluorobenzyl)quinazolin-4(3H)-one (CAS 302913-38-8)
- Benzenesulfonyl fluoride, 3-(chlorosulfonyl)-4-methoxy- (CAS 97903-70-3)
- 5-Chloro-2-(4-fluorobenzoyl)-3-methyl-1-benzofuran (CAS 306979-07-7)
- Diethyl 2-(4-chloro-2-fluorophenyl)malonate (CAS 680211-90-9)
- 2-(2,6-Dichlorobenzyl)oxazole-4-carboxylic Acid (CAS 736971-96-3)
- Methyl 2,2-dimethyl-6-methylenecyclohexanecarboxylate (CAS 81752-87-6)
- 4-Chloro-3-fluoro-2-methylphenol (CAS 1804404-46-3)
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- Gibberellin A4-d2 (CAS CATO-CCHM705926)
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- 2,2',2'',2'''-(2-(4-Aminobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (CAS 123317-52-2)
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- rac-(3’aR,6’aS)-5,5-dimethyl-hexahydro-1’H-spiro[1,3-dioxane-2,2’-pentalene]-5’-ol (CAS 208347-37-9)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
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