2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]acetamide CAS 554405-16-2

Purity 97%+In StockPharmaceutical Standards
CAS No.554405-16-2
Molecular FormulaC11H7ClF2N2OS
Molecular Weight288.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]acetamide CAS 554405-16-2 chemical structure

Description

As a certified reference material (CRM), 2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]acetamide (CAS 554405-16-2) is a high-purity analytical reference standard with the molecular formula C11H7ClF2N2OS and a molecular weight of 288.70 g/mol.

2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]acetamide (C11H7ClF2N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H7ClF2N2OS
Molecular Weight288.70 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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