2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide CAS 303091-53-4

Purity 97%+In StockPharmaceutical Standards
CAS No.303091-53-4
Molecular FormulaC18H19ClFN3O
Molecular Weight347.81 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide CAS 303091-53-4 chemical structure

Description

The occurrence of 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide (CAS 303091-53-4), molecular formula C18H19ClFN3O and molecular weight 347.81 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide (C18H19ClFN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 347.81 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H19ClFN3O
Molecular Weight347.81 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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