N-(3-chlorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide CAS 329080-06-0
| CAS No. | 329080-06-0 |
| Molecular Formula | C18H19ClFN3O |
| Molecular Weight | 347.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3-chlorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 329080-06-0) is a high-purity analytical reference standard with the molecular formula C18H19ClFN3O and a molecular weight of 347.81 g/mol.
Based on its molecular formula C18H19ClFN3O, N-(3-chlorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3-chlorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19ClFN3O |
| Molecular Weight | 347.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-fluorophenyl)acetamide (CAS 303091-53-4)
- N-(4-chlorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 882081-57-4)
- 2-(2-((3-Chlorophenyl)amino)thiazol-4-yl)-N-(furan-2-ylmethyl)acetamide (CAS 1040655-37-5)
- 5-(2-Chlorophenyl)-4-(2,4-dimethoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 1172816-79-3)
- 4-(3-Chlorophenyl)-N-(p-tolyl)-1H-pyrazole-5-sulfonamide (CAS 1239479-86-7)
- 1-(4-(2-Chlorophenyl)-5-methylisoxazole-3-carbonyl)piperidine-4-carboxamide (CAS 6146-75-4)
- 1-(4-Chlorophenyl)-3-(4-ethyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)pyridazin-4(1H)-one (CAS 478077-60-0)
- 3-(2-(4-Chlorophenyl)hydrazono)-1-phenylindolin-2-one (CAS 303984-90-9)
Recommended Standards
- N-(3-chloro-4-fluorophenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 303091-00-1)
- N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide (CAS 553657-57-1)
- 1-((5-Chloro-2-ethoxyphenyl)sulfonyl)piperidine-4-carboxylic acid (CAS 915909-89-6)
- SulfoxFluor (CAS 2143892-50-4)
- 2-Hydrazinyl-1-methyl-1h-benzo[d]imidazole (CAS 7022-37-9)
- 4-(5-Trifluoromethyl-pyridin-2-yl)-benzoyl chloride (CAS 223128-27-6)
- N-((1-Benzylpiperidin-3-yl)methyl)propan-2-amine (CAS 1273848-19-3)
- 4-Methyl-N-((pyridin-4-ylmethyl)carbamoyl)benzenesulfonamide (CAS 401576-44-1)
- 2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid (CAS 1352813-46-7)
- N-Cyclobutyl-5-methyl-1,3,4-thiadiazol-2-amine (CAS 1466866-93-2)
- 2-fluoro-6-oxo-5H-benzo[b][1,4]benzothiazepine-3-carboxylic acid (CAS 1809143-47-2)
- 2-(2,3-Difluorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene (CAS 898778-73-9)
- Tert-butyl (2,2,3,3-tetramethylcyclopropyl)carbamate (CAS 1499405-44-5)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
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