N-(4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide CAS 303091-62-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide.

N-(4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 303091-62-5), molecular formula C18H19F2N3O and molecular weight 331.36 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (C18H19F2N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-fluorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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