N-(4-Chlorophenyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide CAS 303093-24-5
| CAS No. | 303093-24-5 |
| Molecular Formula | C19H17ClN2O3 |
| Molecular Weight | 356.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(4-Chlorophenyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(4-Chlorophenyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide (CAS 303093-24-5), molecular formula C19H17ClN2O3 and molecular weight 356.80 g/mol, is a CATO reference standard with documented purity and traceability.
N-(4-Chlorophenyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide (C19H17ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Chlorophenyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17ClN2O3 |
| Molecular Weight | 356.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 2-((4-(2-(2-Chlorophenyl)acetamido)but-2-yn-1-yl)oxy)benzamide (CAS 1421442-94-5)
- (E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-cyano-N-((tetrahydrofuran-2-yl)methyl)acrylamide (CAS 444764-47-0)
- 4-(4-Chlorophenyl)-3-phenylisoxazolo[4,5-c]quinoline (CAS 253433-32-8)
- Ethyl 2-{3-[(4-chlorophenyl)methyl]-4-oxo-3,4-dihydrophthalazin-1-yl}acetate (CAS 866151-32-8)
- Ethyl 4-(4-chlorophenyl)-6-hydroxy-2-phenyl-4,5-dihydropyrimidine-5-carboxylate (CAS 400078-28-6)
- N-(2-chlorophenyl)-2-((4-fluorophenyl)sulfonamido)propanamide (CAS 317378-04-4)
- (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-({[(pyridin-3-yl)methyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-19-2)
- 1-(3-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea (CAS 325850-26-8)
Recommended Standards
- 1-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperazin-1-yl)-2-(2-chlorophenyl)ethan-1-one (CAS 1058447-61-2)
- N-(2-Chlorobenzyl)-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 303093-42-7)
- 9-(4-Chloro-6-phenyl-1,3,5-triazin-2-yl)-9H-carbazole (CAS 1268244-56-9)
- Methyl 4-({[(3Z)-1-(4-chlorophenyl)-2-oxopyrrolidin-3-ylidene]methyl}amino)benzoate (CAS 339020-60-9)
- Methyl 2-(methylthio)pyrimidine-5-carboxylate (CAS 38275-41-1)
- (4-(4-(Trifluoromethoxy)phenoxy)phenyl)methanol (CAS 1686102-84-0)
- 2-[1-(2-amino-1,3-thiazol-4-yl)ethyl]-2,3-dihydro-1h-isoindole-1,3-dione (CAS 1240790-65-1)
- Chlorpromazine EP Impurity A HCl (CAS 316-07-4)
- 1-(Pyridin-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (CAS 3380-84-5)
- 6-(Furan-2-yl)-3-((pyridin-3-ylmethyl)thio)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 891099-01-7)
- 1-(1-Aminoethyl)tricyclo[3.3.1.13,7]decan-2-ol 127619-49-2 2-(|A,|A)-Hydroxy Rimantadine (CAS 127619-49-2)
- 3-Chloro-n-{2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}propanamide (CAS 950124-73-9)
- 4-(Difluoromethyl)-3-nitropyridine (CAS 1805302-16-2)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com