(E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-cyano-N-((tetrahydrofuran-2-yl)methyl)acrylamide CAS 444764-47-0
| CAS No. | 444764-47-0 |
| Molecular Formula | C19H17ClN2O3 |
| Molecular Weight | 356.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-cyano-N-((tetrahydrofuran-2-yl)methyl)acrylamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-cyano-N-((tetrahydrofuran-2-yl)methyl)acrylamide (CAS 444764-47-0), molecular formula C19H17ClN2O3 and molecular weight 356.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-cyano-N-((tetrahydrofuran-2-yl)methyl)acrylamide (C19H17ClN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-cyano-N-((tetrahydrofuran-2-yl)methyl)acrylamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H17ClN2O3 |
| Molecular Weight | 356.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 2-((4-(2-(2-Chlorophenyl)acetamido)but-2-yn-1-yl)oxy)benzamide (CAS 1421442-94-5)
- 4-(4-Chlorophenyl)-3-phenylisoxazolo[4,5-c]quinoline (CAS 253433-32-8)
- Ethyl 2-{3-[(4-chlorophenyl)methyl]-4-oxo-3,4-dihydrophthalazin-1-yl}acetate (CAS 866151-32-8)
- Ethyl 4-(4-chlorophenyl)-6-hydroxy-2-phenyl-4,5-dihydropyrimidine-5-carboxylate (CAS 400078-28-6)
- N-(2-chlorophenyl)-2-((4-fluorophenyl)sulfonamido)propanamide (CAS 317378-04-4)
- N-(4-Chlorophenyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide (CAS 303093-24-5)
- (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-({[(pyridin-3-yl)methyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-19-2)
- 1-(3-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea (CAS 325850-26-8)
Recommended Standards
- N-Benzyl-2-chloro-N-(2,5-dioxo-1-phenylpyrrolidin-3-yl)acetamide (CAS 1858240-51-3)
- 1-(2-Chlorobenzyl)-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 590357-02-1)
- 1-(4-Chlorobenzyl)-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 588676-84-0)
- 2-(4-Chloro-2-(1-phenyl-1H-pyrazol-5-yl)phenoxy)ethyl acetate (CAS 141355-87-5)
- 83016-75-5 2-Propanol, 1-(phenylmethoxy)-3-(2-propenyloxy)- DTXSID40444383 (CAS 83016-75-5)
- 1-(Bromomethyl)-1-(isopropoxymethyl)cyclobutane (CAS 1464983-52-5)
- 4-(4-Methoxyphenyl)phenol (CAS 16881-71-3)
- 1-(6-Bromopyridin-2-yl)pyrrolidin-3-amine hydrochloride, 95% (CAS 1420963-04-7)
- 1,1-Dimethyl-3-(octahydro-1H-4,7-methanoinden-2-yl)urea (CAS 3703-48-8)
- 2,3-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 2377610-94-9)
- Methyl 3-((4-methoxyphenyl)amino)benzoate (CAS 579510-29-5)
- (1-Cyclohexyl-4-(cyclohexylamino)-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone (CAS 55933-66-9)
- 5-Iodothiazole-2-carbonitrile (CAS 1807233-64-2)
- Cholecystokinin Octapeptide (1-5) (desulfated) (CAS 121880-96-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com