3-((2-Chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one CAS 303144-58-3
| CAS No. | 303144-58-3 |
| Molecular Formula | C13H11ClFNO2 |
| Molecular Weight | 267.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one.
CATO supplies 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one (CAS 303144-58-3), a certified reference material (molecular formula C13H11ClFNO2, MW 267.68 g/mol) for analytical method development and quality control.
3-((2-Chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one (C13H11ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11ClFNO2 |
| Molecular Weight | 267.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-(4-Chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propan-1-amine (CAS 1006454-49-4)
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- Ethyl 4-chloro-5-fluoro-8-methylquinoline-3-carboxylate (CAS 1019462-75-9)
- 3-Acetyl-7-chloro-1-ethyl-6-fluoroquinolin-4(1H)-one (CAS 105892-51-1)
- (2-Chloro-benzyl)-(3-trifluoromethoxy-propyl)-amine (CAS 1208079-73-5)
- (R)-1-(3-chloro-4-(trifluoromethoxy)phenyl)-2-methylpropan-1-amine (CAS 1213016-11-5)
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Recommended Standards
- 2-Chloro-4-fluoro-3-[(4-methoxyphenyl)methoxy]pyridine (CAS 2869955-42-8)
- N1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N2,N2-dimethylethane-1,2-diamine (CAS 338406-27-2)
- (3AR,4S,9bS)-8-chloro-6-fluoro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid (CAS 956628-90-3)
- Vonoprazan Impurity 131 (CAS 881674-01-7)
- N-Benzyl-4,6-difluoro-1,3-benzothiazol-2-amine (CAS 941867-18-1)
- 4-(Aminomethyl)-N-(1-phenylethyl)oxan-4-amine (CAS 1306605-25-3)
- 6-Ethyl-3-(((pyridin-3-ylmethyl)amino)methyl)quinolin-2(1H)-one (CAS 436087-69-3)
- 2,4,6-Trimethylpyrimidin-5-ol (CAS 71267-12-4)
- 3,3-Difluoroprop-2-en-1-ol (CAS 819-72-7)
- 4-Methoxybenzofuran-6-amine (CAS 1330752-90-3)
- Dichlorprop-Methyl Ester (CAS 23844-57-7)
- 1-(2-Isopropoxypyridin-3-yl)ethanone (CAS 1551553-85-5)
- 6-(4-Chlorophenyl)-2-(2,4-dichlorophenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-47-6)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
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