(5E)-4-Chloro-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-5H-1,2,3-dithiazol-5-imine CAS 303146-02-3
| CAS No. | 303146-02-3 |
| Molecular Formula | C14H6Cl2F3N3OS2 |
| Molecular Weight | 424.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5E)-4-Chloro-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-5H-1,2,3-dithiazol-5-imine.
CATO supplies (5E)-4-Chloro-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-5H-1,2,3-dithiazol-5-imine (CAS 303146-02-3), a certified reference material (molecular formula C14H6Cl2F3N3OS2, MW 424.25 g/mol) for analytical method development and quality control.
The molecular framework of (5E)-4-Chloro-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-5H-1,2,3-dithiazol-5-imine (C14H6Cl2F3N3OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H6Cl2F3N3OS2 |
| Molecular Weight | 424.25 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related E Standards
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Recommended Standards
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- Crisaborole lmpurity 75 (CAS CATO-C4X-202175)
- 1-((4-Bromobenzyl)oxy)-6-nitro-2-phenyl-1H-benzo[d]imidazole (CAS 303148-89-2)
- 5-bromo-1H-indole-2-carboxamide (CAS 877371-97-6)
- 4-Bromo-n-(2-iodophenyl)benzenesulfonamide (CAS 349404-93-9)
- (R)-2-Ethynylpiperidine (CAS 128959-93-3)
- 4-Chloro-1-(cyclohexylmethyl)-2-methylbenzene (CAS 1369910-77-9)
- 4,6-Dichloro-5-(4-methoxyphenyl)pyrimidine (CAS 146533-56-4)
- 3-Isopropoxypiperidine (CAS 1220175-72-3)
- N,N'-Bis(3-hydroxypropyl)homopiperazine (CAS 19970-80-0)
- 4-Hydroxy-2,3-dihydro-1H-indene-5-carbaldehyde (CAS 1092553-18-8)
- 6-Nitroquinoline-5-carbaldehyde (CAS 101327-86-0)
- Hexapeptide-9 (CAS 885024-94-2)
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