1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[2-(4-chlorophenyl)acetyl]-1H-pyrrole-2-carbonitrile CAS 338406-99-8
| CAS No. | 338406-99-8 |
| Molecular Formula | C19H10Cl2F3N3O |
| Molecular Weight | 424.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[2-(4-chlorophenyl)acetyl]-1H-pyrrole-2-carbonitrile is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[2-(4-chlorophenyl)acetyl]-1H-pyrrole-2-carbonitrile (CAS 338406-99-8) is a high-purity analytical reference standard with the molecular formula C19H10Cl2F3N3O and a molecular weight of 424.20 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[2-(4-chlorophenyl)acetyl]-1H-pyrrole-2-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 424.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[2-(4-chlorophenyl)acetyl]-1H-pyrrole-2-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H10Cl2F3N3O |
| Molecular Weight | 424.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- N1-{4-[2-chloro-5-(trifluoromethyl)phenoxy]-2-fluorophenyl}-3-chloro-2,2-dimethylpropanamide (CAS 243963-31-7)
- (3S)-7-Chloro-1-(5-chloro-4-methoxy-2-nitrophenyl)-6-fluoro-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (CAS 1958821-59-4)
- (5E)-4-Chloro-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-5H-1,2,3-dithiazol-5-imine (CAS 303146-02-3)
- (5Z)-4-Chloro-N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-5H-1,2,3-dithiazol-5-imine (CAS 306979-52-2)
- 3-(2-Chloro-4-(4-chlorophenoxy)phenyl)-N-phenyl-1H-pyrazole-1-carboxamide (CAS 321522-24-1)
- 3-((4-Chloro-3-methylphenoxy)methyl)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole (CAS 141079-07-4)
- N-(4-chloro-2,5-dimethoxyphenyl)-2-(4-(3-chlorophenyl)piperazin-1-yl)acetamide (CAS 720667-90-3)
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