1-{7-[(E)-2-(4-chlorophenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-1H-pyrrole CAS 303146-14-7
| CAS No. | 303146-14-7 |
| Molecular Formula | C17H12ClN5 |
| Molecular Weight | 321.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-{7-[(E)-2-(4-chlorophenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-1H-pyrrole (CAS 303146-14-7), molecular formula C17H12ClN5 and molecular weight 321.76 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-{7-[(E)-2-(4-chlorophenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-1H-pyrrole (C17H12ClN5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 321.76 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-{7-[(E)-2-(4-chlorophenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-1H-pyrrole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H12ClN5 |
| Molecular Weight | 321.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related E Standards
- Ethyl 2-[1-(3-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]-2-(n-hydroxyimino)acetate (CAS 1006482-03-6)
- 1-(2-Chlorophenyl)-3-(4-(dimethylamino)-2-methoxypyrimidin-5-yl)urea (CAS 1797659-87-0)
- N-(3-Chlorophenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 196504-86-6)
- 3-(2-Chlorophenyl)-5-[(E)-2-(phenylamino)ethenyl]-1,2-oxazole-4-carbonitrile (CAS 320424-89-3)
- 4-(1-(3-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl)piperazine-1-carbaldehyde (CAS 311783-16-1)
- 4-(1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl)piperazine-1-carbaldehyde (CAS 311793-29-0)
- 4-(4-Chlorophenyl)-6-(methylamino)-2-(pyridin-3-yl)pyrimidine-5-carbonitrile (CAS 320417-54-7)
- 5-(4-Chlorophenyl)-2-((4-hydroxyisoxazolidin-2-yl)methylene)cyclohexane-1,3-dione (CAS 338422-55-2)
Recommended Standards
- (2-Amino-5-chlorophenyl)(3,4,5-trimethoxyphenyl)methanone (CAS 313496-54-7)
- 2-((2-Chloro-6-fluorobenzyl)thio)-5-(pyridin-4-yl)-1,3,4-oxadiazole (CAS 477856-79-4)
- 3-Benzyl-7-chloro-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 433922-12-4)
- 4-Chloro-2-(4-(ethoxycarbonyl)-1,5-dimethyl-1H-pyrrol-2-yl)benzoic acid (CAS 1644543-61-2)
- 7-Chloro-2-ethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole (CAS 2409580-00-1)
- Methyl 8-methoxy-2-nitroindolizine-7-carboxylate (CAS 1706443-17-5)
- 3-Aminocyclohexyl acetate (CAS 1449010-07-4)
- N-(2,5-Dibromopyridin-3-yl)methanesulfonamide (CAS 2762349-36-8)
- 4-amino-1-benzyl-5-methylpyrrolidin-2-one hydrochloride (CAS 1803567-17-0)
- 2-(3-Aminophenyl)propanoic acid (CAS 21762-11-8)
- 4-Pyridinebutanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αR)- (CAS 1227940-30-8)
- 4-Cyclohexylbutan-2-amine (CAS 791752-94-8)
- 5-Bromo-2,4-dimethoxybenzyl alcohol (CAS 181819-62-5)
- Semaglutide Impurity 5 (CAS 23406-82-8)
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