5-(4-Chlorophenyl)-2-((4-hydroxyisoxazolidin-2-yl)methylene)cyclohexane-1,3-dione CAS 338422-55-2
| CAS No. | 338422-55-2 |
| Molecular Formula | C16H16ClNO4 |
| Molecular Weight | 321.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorophenyl)-2-((4-hydroxyisoxazolidin-2-yl)methylene)cyclohexane-1,3-dione (C16H16ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(4-Chlorophenyl)-2-((4-hydroxyisoxazolidin-2-yl)methylene)cyclohexane-1,3-dione (CAS 338422-55-2), molecular formula C16H16ClNO4 and molecular weight 321.76 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Chlorophenyl)-2-((4-hydroxyisoxazolidin-2-yl)methylene)cyclohexane-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO4 |
| Molecular Weight | 321.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-Chloro-N-(4-ethylcyclohexyl)acetamide (CAS 915924-28-6)
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- 2-(Trifluoromethyl)benzo[d]thiazole-6-carbaldehyde (CAS 933693-18-6)
- Ethyl 3-chloro-4-oxopiperidine-1-carboxylate (CAS 89424-04-4)
- 1-(2-Fluoroethyl)-1H-pyrazole-5-carboxylic acid (CAS 1198437-45-4)
- (4-Iodo-1,3-dimethyl-1H-pyrazol-5-yl)methanol, 97% (CAS 1356998-41-8)
- 4-(2,2-Dimethoxyethyl)benzonitrile (CAS 186826-34-6)
- 3-Fluorobutane-1-sulfonyl chloride (CAS 1785492-58-1)
- 1-Bromo-2-((2-ethylhexyl)oxy)cyclopentane (CAS 1339569-77-5)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
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