2-[(4-Chlorophenyl)methyl]-N-[(2,4-dichlorophenyl)methyl]quinazolin-4-amine CAS 303149-83-9
| CAS No. | 303149-83-9 |
| Molecular Formula | C22H16Cl3N3 |
| Molecular Weight | 428.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[(4-Chlorophenyl)methyl]-N-[(2,4-dichlorophenyl)methyl]quinazolin-4-amine.
CATO supplies 2-[(4-Chlorophenyl)methyl]-N-[(2,4-dichlorophenyl)methyl]quinazolin-4-amine (CAS 303149-83-9), a certified reference material (molecular formula C22H16Cl3N3, MW 428.74 g/mol) for analytical method development and quality control.
2-[(4-Chlorophenyl)methyl]-N-[(2,4-dichlorophenyl)methyl]quinazolin-4-amine (C22H16Cl3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl3N3 |
| Molecular Weight | 428.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-[(4-Chlorophenyl)methyl]-N-[(3,4-dichlorophenyl)methyl]quinazolin-4-amine (CAS 303149-57-7)
- 4-(4-Chlorophenyl)-6-(3,4-dichlorophenyl)-2-(pyrrolidin-1-yl)pyridine-3-carbonitrile (CAS 303984-53-4)
- 3-(4-Chlorophenyl)-N-(3,4-dichlorophenyl)-5-(methylsulfanyl)thiophene-2-carboxamide (CAS 477858-04-1)
- N-(4-chlorophenyl)-3-((2,4-dichlorobenzyl)thio)thiophene-2-carboxamide (CAS 251097-46-8)
- N-(4-chlorophenyl)-3-((3,4-dichlorobenzyl)thio)thiophene-2-carboxamide (CAS 250714-58-0)
- N-(4-Chlorophenyl)-3-{[(2,6-dichlorophenyl)methyl]sulfanyl}thiophene-2-carboxamide (CAS 251096-91-0)
- 4-(3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-2-(3,4-dimethylphenyl)phthalazin-1(2H)-one (CAS 478045-66-8)
- 4-(3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-2-(3,4-dimethylphenyl)phthalazin-1(2H)-one (CAS 478045-68-0)
Recommended Standards
- Epifriedelanol (CAS 16844-71-6)
- (10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 911660-54-3 (CAS 911660-54-3)
- Friedelan-3a-ol (CAS 5085-72-3)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-cyanopropan-2-yl 3-nitrobenzoate (CAS 339016-44-3)
- 3,5-Dichloro-6-fluoro-N,N-dimethylpyrazin-2-amine (CAS 55233-63-1)
- (R)-5-Fluoro-2-(pyrrolidin-2-yl)-1H-benzo[d]imidazole (CAS 1311255-18-1)
- {3-[(4-methylpiperazin-1-yl)methyl]phenyl}methanamine (CAS 515162-19-3)
- 1-[4-(Trifluoromethyl)phenyl]ethane-1,2-diol (CAS 175605-64-8)
- 2-(Pyrimidin-4-ylamino)acetic acid (CAS 72971-95-0)
- Methyl 5-(chloromethyl)-2-methylfuran-3-carboxylate (CAS 35351-32-7)
- 1-Allyl-3-nitro-1H-1,2,4-triazole (CAS 371201-70-6)
- 2-(azetidin-3-yl)propan-2-amine;dihydrochloride (CAS 2411641-80-8)
- 1-(2-(6-Amino-4-methylpyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352535-93-3)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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