(E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)[(4-chlorophenyl)methoxy]amine CAS 303150-51-8
| CAS No. | 303150-51-8 |
| Molecular Formula | C19H15Cl2F3N4O |
| Molecular Weight | 443.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)[(4-chlorophenyl)methoxy]amine.
(E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)[(4-chlorophenyl)methoxy]amine (CAS 303150-51-8) is a high-purity analytical reference standard with the molecular formula C19H15Cl2F3N4O and a molecular weight of 443.25 g/mol.
Structurally, (E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)[(4-chlorophenyl)methoxy]amine (C19H15Cl2F3N4O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 443.25 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)[(4-chlorophenyl)methoxy]amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H15Cl2F3N4O |
| Molecular Weight | 443.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 4-Chloro-N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}phenyl)benzamide (CAS 338407-33-3)
- 8-Chloro-5-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one (CAS 303986-21-2)
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Recommended Standards
- 2-Iodo-6-methyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227268-96-3)
- 2-(2-(2-((1-Bromonaphthalen-2-yl)oxy)acetyl)hydrazine-1-carbonyl)benzoic acid (CAS 328025-20-3)
- 4-Bromo-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-3H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione (CAS 851659-01-3)
- 5-Bromo-2-chloro-1,3-diiodobenzene (CAS 2383588-60-9)
- 3-(4-Fluorobenzylidene)chroman-4-one (CAS 193406-85-8)
- tert-Butyl 2-oxo-3-oxa-1,9-diazaspiro[5.5]undecane-9-carboxylate (CAS 1363383-43-0)
- Dicyclohexyl(methyl)phosphine oxide (CAS 42366-52-9)
- (Tris(diethylamino)-l5-phosphaneylidene)triaz-1-yn-2-ium Bromide (CAS 130888-29-8)
- 4-((4-Chloro-3,5-dimethylphenoxy)methyl)benzohydrazide (CAS 832740-36-0)
- 2-hydroxypent-3-enoic acid (CAS 78119-42-3)
- Delafloxacin Impurity 18 (CAS CATO-C4X-263718)
- 1-(Difluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1216244-84-6)
- Ethyl 5,7-dichloro-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylate (CAS 1053656-63-5)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
Why CATO?
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