Methyl 2-(2-(4-(tert-butyl)phenoxy)-2,2-difluoroacetamido)benzoate CAS 303151-27-1
| CAS No. | 303151-27-1 |
| Molecular Formula | C20H21F2NO4 |
| Molecular Weight | 377.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 377.38 g/mol gives Methyl 2-(2-(4-(tert-butyl)phenoxy)-2,2-difluoroacetamido)benzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-(2-(4-(tert-butyl)phenoxy)-2,2-difluoroacetamido)benzoate (CAS 303151-27-1) is a high-purity analytical reference standard with the molecular formula C20H21F2NO4 and a molecular weight of 377.38 g/mol.
Structurally, Methyl 2-(2-(4-(tert-butyl)phenoxy)-2,2-difluoroacetamido)benzoate (C20H21F2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 377.38 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 2-(2-(4-(tert-butyl)phenoxy)-2,2-difluoroacetamido)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21F2NO4 |
| Molecular Weight | 377.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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