2-(4-tert-Butylphenoxy)-2,2-difluoro-N-(prop-2-en-1-yl)acetamide CAS 303151-29-3

Purity 97%+In StockPharmaceutical Standards
CAS No.303151-29-3
Molecular FormulaC15H19F2NO2
Molecular Weight283.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-tert-Butylphenoxy)-2,2-difluoro-N-(prop-2-en-1-yl)acetamide CAS 303151-29-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 283.31 g/mol gives 2-(4-tert-Butylphenoxy)-2,2-difluoro-N-(prop-2-en-1-yl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(4-tert-Butylphenoxy)-2,2-difluoro-N-(prop-2-en-1-yl)acetamide (CAS 303151-29-3) is a high-purity analytical reference standard with the molecular formula C15H19F2NO2 and a molecular weight of 283.31 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-tert-Butylphenoxy)-2,2-difluoro-N-(prop-2-en-1-yl)acetamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 283.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H19F2NO2
Molecular Weight283.31 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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