Ethyl 2-(2-acetyl-5-chlorophenoxy)acetate CAS 30335-94-5
| CAS No. | 30335-94-5 |
| Molecular Formula | C12H13ClO4 |
| Molecular Weight | 256.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 2-(2-acetyl-5-chlorophenoxy)acetate (C12H13ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ethyl 2-(2-acetyl-5-chlorophenoxy)acetate (CAS 30335-94-5), molecular formula C12H13ClO4 and molecular weight 256.68 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13ClO4 |
| Molecular Weight | 256.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
Recommended Standards
- Butanedioic acid, 2-(4-chlorophenyl)-, 1,4-dimethyl ester (CAS 36122-30-2)
- Ethyl 3-(2-chloro-4-methoxyphenyl)-3-oxopropanoate (CAS 941696-11-3)
- Benzofuran-2-yl(4-chlorophenyl)methanone (CAS 27052-20-6)
- Ethyl 4-(4-chlorophenoxy)-3-oxobutanoate (CAS 97900-77-1)
- Methyl 3-oxo-2,3-dihydro-1H-indazole-5-carboxylate (CAS 1082041-20-0)
- 1-(4-Methoxyphenyl)-3-[(pyridin-3-yl)methyl]thiourea (CAS 405067-52-9)
- 4-[(2-Phenoxyethyl)amino]butanoic acid (CAS 1016531-72-8)
- N-(2-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-4-yl)propionamide (CAS 50981-11-8)
- 9-(Diethylamino)-3-hydroxy-5H-benzo[a]phenoxazin-5-one (CAS 93397-90-1)
- (4-(1-Methyl-1H-pyrazol-4-yl)phenyl)methanol (CAS 88751-41-1)
- Ethyl 6-methyl-2-(trifluoromethyl)pyrimidine-4-carboxylate (CAS 945717-60-2)
- (6-Aminopyridin-3-yl)(pyrrolidin-1-yl)methanone (CAS 218631-50-6)
- Ethinylestradiol EP Impurity H (CAS 1350468-76-6)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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