Sofosbuvir Impurity 88 CAS 30361-19-4
| CAS No. | 30361-19-4 |
| Molecular Formula | C34H28O9 |
| Molecular Weight | 580.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Sofosbuvir Impurity 88 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 580.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Sofosbuvir Impurity 88 (CAS 30361-19-4, C34H28O9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H28O9 |
| Molecular Weight | 580.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 56 (CAS 1496551-70-2)
- Sofosbuvir Impurity 10 (CAS CATO-C4X-105210)
- Sofosbuvir Impurity 11 (CAS CATO-C4X-105211)
- Sofosbuvir Impurity 4 (CAS 874638-94-5)
- Sofosbuvir Impurity 5 (CAS CATO-C4X-10525)
- Sofosbuvir Impurity 6 (CAS CATO-C4X-10526)
- Sofosbuvir Impurity 7 (CAS CATO-C4X-10527)
- Sofosbuvir Impurity 72 (CAS CATO-C4X-105272)
Recommended Standards
- Setomimycin (CAS 69431-87-4)
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- Acanthoside B (CAS 7374-79-0)
- (R)-C2-TunaPhos (CAS 301847-88-1)
- Epinephrine /Adrenaline Impurity 135 (CAS CATO-C4X-1849135)
- Ertapenem impurity 47 (CAS CATO-C4X-163347)
- N-Nitroso Cinacalcet Impurity 3 (CAS CATO-C4X-105973)
- 1H-pyrrolo[3,2-c]pyridine-4-carboxylic acid hydrochloride (CAS 1864063-95-5)
- 207556-12-5 Methyl-13C triflate Methyl-13C trifluoromethane sulfonate (CAS 207556-12-5)
- Ethyl 5-amino-3-(2-ethoxy-2-oxoethyl)isoxazole-4-carboxylate (CAS 82754-70-9)
- 5-Methoxy-2-methylpyrazolo[1,5-a]pyridine-3-carboxylic acid (CAS 1352395-28-8)
- Vinorelbine Impurity 14 (CAS CATO-C4X-264214)
- Trichlorocarbonylbis(triphenylphosphine)rhenium(V) (CAS 17442-18-1)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
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