3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isopentylquinolin-2(1H)-one CAS 303776-89-8
| CAS No. | 303776-89-8 |
| Molecular Formula | C21H21N3O4S |
| Molecular Weight | 411.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isopentylquinolin-2(1H)-one.
CATO supplies 3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isopentylquinolin-2(1H)-one (CAS 303776-89-8), a certified reference material (molecular formula C21H21N3O4S, MW 411.47 g/mol) for analytical method development and quality control.
The molecular framework of 3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isopentylquinolin-2(1H)-one (C21H21N3O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isopentylquinolin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21N3O4S |
| Molecular Weight | 411.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dioxido Standards
- 2-{[(1,1-Dioxido-1,2-benzisothiazol-3-yl)-(1-naphthyl)amino]methyl}phenol (CAS 442571-99-5)
- Ethyl 2-(4-(1,1-dioxido-1,2-thiazinan-2-yl)benzamido)benzoate (CAS 941900-47-6)
- 3-[(1,1-Dioxido-1,2-benzisothiazol-3-yl)amino]-phenyl 2-bromobutanoate (CAS 1192805-64-3)
- 1-Butyl-3-(1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone 303776-83-2 (CAS 303776-83-2)
- 5-(5,5-Dioxido-10H-phenothiazin-10-yl)isophthalicacid (CAS 2357185-47-6)
- 2-[(1,1-Dioxido-1,2-benzisothiazol-3-yl)(4-methoxybenzyl)amino]phenol (CAS 663199-63-1)
- Ethyl 1-(3-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)propanoyl)piperidine-4-carboxylate (CAS 899995-80-3)
- 3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-7-fluoro-4-hydroxy-1-isopentylquinolin-2(1H)-one (CAS 477930-58-8)
Recommended Standards
- (E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide (CAS 873307-21-2)
- 3-(Benzylamino)-4-((4-(4-methoxyphenyl)thiazol-2-yl)amino)-4-oxobutanoic acid (CAS 2096495-93-9)
- Tert-butyl (R)-3-((1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)oxy)pyrrolidine-1-carboxylate (CAS 1354006-88-4)
- 3-(n-Benzyl-n-(2-ethoxyphenyl)sulfamoyl)benzoic acid (CAS 731820-89-6)
- Methyl 5-(benzylsulfanyl)-1,3-thiazole-4-carboxylate (CAS 89502-06-7)
- 2-((3-(Furan-2-ylmethyl)-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 878683-66-0)
- 5-Amino-5-methylhexanoic acid (CAS 933753-22-1)
- N-(5-Cyclopropoxy-2-isopropylpyridin-3-yl)methanesulfonamide (CAS 1243371-07-4)
- 4-Amino-5-(pentyloxy)furan-2(5H)-one (CAS 370876-78-1)
- 6-Methyl-5-phenylthiazolo[3,2-b][1,2,4]triazole (CAS 1423121-02-1)
- Ethyl 3-(1,3-dichloropropyl)[1,2,4]triazolo[4,3-a]pyridine-8-carboxylate (CAS 1353506-05-4)
- 4-hydroxy-1,2-dimethylpyrrolidine-2-carboxylic acid hydrochloride (CAS 2044712-62-9)
- n-[4-(2-chloroacetyl)-2-(methylsulfanyl)phenyl]acetamide (CAS 1146290-42-7)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
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