(E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide CAS 873307-21-2
| CAS No. | 873307-21-2 |
| Molecular Formula | C21H21N3O4S |
| Molecular Weight | 411.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide.
CATO supplies (E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide (CAS 873307-21-2), a certified reference material (molecular formula C21H21N3O4S, MW 411.47 g/mol) for analytical method development and quality control.
The molecular framework of (E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide (C21H21N3O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21N3O4S |
| Molecular Weight | 411.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- Tert-butyl (R)-3-((1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)oxy)pyrrolidine-1-carboxylate (CAS 1354006-88-4)
- 3-(1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isopentylquinolin-2(1H)-one (CAS 303776-89-8)
- 13:0 Lyso PE (CAS 1223068-83-4)
- 3-(Benzylamino)-4-((4-(4-methoxyphenyl)thiazol-2-yl)amino)-4-oxobutanoic acid (CAS 2096495-93-9)
- 6-Chloro-6-heptenenitrile (CAS 148252-47-5)
- Ethyl 2-(2-(4-(2-hydroxyethyl)piperazin-1-yl)acetamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 446280-91-7)
- 3-[(2-fluorophenyl)methyl]-1-[(4-methylbenzene)sulfonyl]azetidine (CAS 1356739-43-9)
- 4,7-Dimethylisoquinoline (CAS 102878-56-8)
- 7-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1094260-88-4)
- Methyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline-4-carboxylate (CAS 2247162-79-2)
- Methyl (3r)-3-amino-3-[2-(trifluoromethyl)phenyl]propanoate (CAS 1228550-48-8)
- Tetranor-PGEM (CAS 24769-56-0)
- N-(3-Cyanophenyl)-5-methylisoxazole-4-carboxamide (CAS 61643-45-6)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com