1-[3-(Trifluoromethyl)benzyl]-1H-indole-2,3-dione 3-(N-phenylhydrazone) CAS 303985-34-4
| CAS No. | 303985-34-4 |
| Molecular Formula | C22H16F3N3O |
| Molecular Weight | 395.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-[3-(Trifluoromethyl)benzyl]-1H-indole-2,3-dione 3-(N-phenylhydrazone) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 395.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-[3-(Trifluoromethyl)benzyl]-1H-indole-2,3-dione 3-(N-phenylhydrazone) (CAS 303985-34-4), molecular formula C22H16F3N3O and molecular weight 395.38 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16F3N3O |
| Molecular Weight | 395.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- N-(2-(3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethyl)benzo[c][1,2,5]thiadiazole-5-carboxamide (CAS 1797671-65-8)
- (3-(Trifluoromethyl)phenyl)(6-(3-(trifluoromethyl)phenyl)pyridin-3-yl)methanone (CAS 860648-91-5)
- 2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(4-methylphenyl)acetonitrile (CAS 478043-26-4)
- 5-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1222533-88-1)
- (1-Methyl-3-(trifluoromethyl)-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazol-4-yl)methyl propionate (CAS 955966-45-7)
- 1897-26-3 2,5-bis(trifluoromethyl)-1,3,4-oxadiazole (CAS 1897-26-3)
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Recommended Standards
- 2-(2-((Benzo[d]1,3-dioxolan-5-ylamino)sulfonyl)-4,5-dimethoxyphenyl)acetic acid (CAS 1797781-96-4)
- 2-((Phenylamino)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 392704-08-4)
- 3-{4-[3-(3-ethyl-1,2-oxazol-5-yl)propoxy]-3,5-dimethylphenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 153168-30-0)
- 7-{[(pyridin-2-yl)amino][4-(trifluoromethyl)phenyl]methyl}quinolin-8-ol (CAS 325474-22-4)
- 5-Bromo-2-(hydroxymethyl)benzoic acid (CAS 627909-55-1)
- N1-(2-aminoethyl)-N1-dodecylethane-1,2-diamine (CAS 4182-44-9)
- 5-(4-(Dimethylamino)phenyl)-3-methyl-5-oxopentanoic acid (CAS 951893-04-2)
- 1-Bromo-3-(3-chloropropyl)benzene (CAS 1057673-67-2)
- 10-Phenyl-1,4-dioxa-7,13-dithia-10-azacyclopentadecane (CAS 240797-81-3)
- 1-(1,3-Dimethyl-1H-pyrazol-5-yl)-N-((3-methyl-1-propyl-1H-pyrazol-4-yl)methyl)methanamine hydrochloride (CAS 1856079-07-6)
- Methyl 3-(2,4-dimethylphenyl)-3-oxopropanoate (CAS 1225915-16-1)
- 5-Amino-6-ethoxypyridin-2-ol (CAS 1094826-68-2)
- N-((5-(Benzofuran-2-yl)isoxazol-3-yl)methyl)cyclopropanecarboxamide (CAS 1105205-53-5)
- Neuropeptide K, porcine (CAS 106441-70-7)
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