2-((Phenylamino)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one CAS 392704-08-4
| CAS No. | 392704-08-4 |
| Molecular Formula | C22H16F3N3O |
| Molecular Weight | 395.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-((Phenylamino)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-((Phenylamino)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 392704-08-4), a certified reference material (molecular formula C22H16F3N3O, MW 395.38 g/mol) for analytical method development and quality control.
The molecular framework of 2-((Phenylamino)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (C22H16F3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H16F3N3O |
| Molecular Weight | 395.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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- N-(4-(2-(Phenylamino)thiazol-4-yl)phenyl)benzamide (CAS 325805-93-4)
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Recommended Standards
- 1-[3-(Trifluoromethyl)benzyl]-1H-indole-2,3-dione 3-(N-phenylhydrazone) (CAS 303985-34-4)
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- 2-(2-((Benzo[d]1,3-dioxolan-5-ylamino)sulfonyl)-4,5-dimethoxyphenyl)acetic acid (CAS 1797781-96-4)
- Morniflumate (CAS 65847-85-0)
- 2-propen-1-ol, polymer with ethenylbenzene 25119-62-4 (CAS 25119-62-4)
- Methyl 4-(4-(methoxycarbonyl)hepta-1,6-diyn-4-yl)benzoate (CAS 1026380-17-5)
- Poly(ethylene Glycol) ~600 (CAS 25322-68-3)
- 2-[4-[2-Amino-3-[2-Amino-3-[4-(Carboxymethyl)Cyclohexyl]Propyl]Disulfanylpropyl]Cyclohexyl]Acetic Acid; 2,2,2-Trifluoroacetic Acid (CAS 156143-99-6)
- 1-(2,3-Dichlorophenyl)-N-methylmethanamine hydrochloride (CAS 39959-78-9)
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- Imidazo[1,2-a]pyrazine-2-carboxylic Acid (CAS 77112-53-9)
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