3-(4-chlorophenyl)-2-cyano-N-[(hydroxyimino)methyl]acrylamide CAS 303994-78-7
| CAS No. | 303994-78-7 |
| Molecular Formula | C11H8ClN3O2 |
| Molecular Weight | 249.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-chlorophenyl)-2-cyano-N-[(hydroxyimino)methyl]acrylamide (CAS 303994-78-7), molecular formula C11H8ClN3O2 and molecular weight 249.65 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H8ClN3O2, 3-(4-chlorophenyl)-2-cyano-N-[(hydroxyimino)methyl]acrylamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 249.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-chlorophenyl)-2-cyano-N-[(hydroxyimino)methyl]acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O2 |
| Molecular Weight | 249.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chlorophenyl Standards
- 5-(4-Chlorophenyl)-2-hydroxyisonicotinic acid (CAS 1261954-43-1)
- 5-(4-Chlorophenyl)-6-hydroxynicotinic acid (CAS 1262010-75-2)
- 1-(2-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1267134-04-2)
- 1-(4-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1267681-65-1)
- 1-(3-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1268028-62-1)
- 1-(3-chlorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 1284635-72-8)
- 5-(3-Chlorophenyl)-3-hydroxypicolinic acid (CAS 1415226-40-2)
- 6-(3-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 147269-19-0)
Recommended Standards
- 3-((6-Chloropyridin-2-yl)oxy)benzoic acid (CAS 866150-72-3)
- 4-(4-Chlorobenzoyl)-1H-pyrrole-2-carboxylic acid (CAS 72531-60-3)
- 2-Nitro-4-chloro-diphenyl Ether (CAS 91-39-4)
- 4-[(5-chloropyridin-2-yl)oxy]benzoic acid (CAS 289044-48-0)
- Methyl 5-methyl-1h-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 1373228-85-3)
- (1r,5r,6s)-6-(Trifluoromethyl)-2-azabicyclo[3.1.0]hexane hydrochloride (CAS 1821706-74-4)
- (R)-5-amino-5-phenylpentanoic acid (CAS 820223-89-0)
- [1-(2-phenylethyl)pyrrolidin-2-yl]methanamine (CAS 60737-45-3)
- 2-methyl-1-benzothiophene-7-carboxylic acid (CAS 75288-80-1)
- Isobutyl 2-(1-butyl-2-oxoindolin-3-ylidene)-7-methyl-3-oxo-5-(thiophen-2-yl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 618078-05-0)
- 1,1'-(2-Hydroxy-4-oxo-4,5-dihydro-1H-pyrrole-1,3-diyl)diethanone (CAS 307925-20-8)
- 3-(4-hydroxypiperidin-1-yl)propanoic acid hydrochloride (CAS 1197502-89-8)
- 2-(2-Oxopyrrolidin-1-yl)isonicotinonitrile (CAS 1949816-64-1)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com