N-(4-chlorophenyl)-N-methyl-1-oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxamide CAS 303995-30-4
| CAS No. | 303995-30-4 |
| Molecular Formula | C23H18ClN3O2 |
| Molecular Weight | 403.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-(4-chlorophenyl)-N-methyl-1-oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxamide (CAS 303995-30-4) is a high-purity analytical reference standard with the molecular formula C23H18ClN3O2 and a molecular weight of 403.86 g/mol.
Structurally, N-(4-chlorophenyl)-N-methyl-1-oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxamide (C23H18ClN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 403.86 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H18ClN3O2 |
| Molecular Weight | 403.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-((1-(4-Chlorophenyl)-1H-tetrazol-5-yl)thio)-N-cyclopropyl-2-(4-fluorophenyl)acetamide (CAS 927147-00-0)
- 2-((3-Chlorophenyl)amino)-9-methyl-3-((2-phenylhydrazono)methyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 326007-30-1)
- 5-(2-Chlorophenyl)-3-hydroxy-1-(1,3,4-thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 406199-93-7)
- N-(3-Chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide (CAS 836640-15-4)
- N-(4-Chlorophenyl)-N-methyl-1-oxo-2-[(pyridin-2-yl)methyl]-1,2-dihydroisoquinoline-4-carboxamide (CAS 303995-37-1)
- 2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,4-dimethoxyphenyl)acetamide (CAS 851078-93-8)
- 2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,5-dimethoxyphenyl)acetamide (CAS 851079-13-5)
- 2-((1-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,4-dimethoxyphenyl)acetamide (CAS 688337-20-4)
Recommended Standards
- N-(4-chlorobenzyl)-2-(1-oxo-4-phenylphthalazin-2(1H)-yl)acetamide (CAS 866153-80-2)
- Trazodone impurity 53 (CAS 1346603-99-3)
- N-(2-Benzylphenyl)-2-(7-chloro-4-oxoquinazolin-3(4H)-yl)acetamide (CAS 853319-00-3)
- Ethyl 4-(chlorosulphonyl)-1,2-diphenyl-5-methyl-1H-pyrrole-3-carboxylate, tech (CAS 1065103-48-1)
- 3-(Aminomethyl)-4-hydroxybenzoic acid hydrochloride (CAS 1047620-71-2)
- Ethyl (E)-3-(2-amino-5-(benzylthio)-4-fluorophenyl)acrylate (CAS 1641578-73-5)
- Methyl 2-(indolin-3-yl)acetate (CAS 85676-99-9)
- (3-Aminopiperidin-1-yl)(2,5-dichlorophenyl)methanone (CAS 1831622-19-5)
- 2'-O-Methylisoliquiritigenin (CAS 51828-10-5)
- 1-(2,2-Dibromoethenyl)-4-nitrobenzene (CAS 51738-10-4)
- (2R)-2-Amino-N-propylpropanamide hydrochloride (CAS 133010-66-9)
- N-(3-Bromo-5-fluorobenzyl)-N-methylcyclobutanamine (CAS 1775205-43-0)
- 2-((4-Cyanobenzyl)(methyl)amino)-N-propylacetamide (CAS 1240816-23-2)
- Vancomycin Hexapeptide (CAS 115236-65-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com