5-(2-Chlorophenyl)-3-hydroxy-1-(1,3,4-thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one CAS 406199-93-7
| CAS No. | 406199-93-7 |
| Molecular Formula | C17H10ClN3O3S2 |
| Molecular Weight | 403.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2-Chlorophenyl)-3-hydroxy-1-(1,3,4-thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one.
5-(2-Chlorophenyl)-3-hydroxy-1-(1,3,4-thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 406199-93-7) is a high-purity analytical reference standard with the molecular formula C17H10ClN3O3S2 and a molecular weight of 403.86 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(2-Chlorophenyl)-3-hydroxy-1-(1,3,4-thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 403.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2-Chlorophenyl)-3-hydroxy-1-(1,3,4-thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H10ClN3O3S2 |
| Molecular Weight | 403.86 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 2-((1-(4-Chlorophenyl)-1H-tetrazol-5-yl)thio)-N-cyclopropyl-2-(4-fluorophenyl)acetamide (CAS 927147-00-0)
- 2-((3-Chlorophenyl)amino)-9-methyl-3-((2-phenylhydrazono)methyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 326007-30-1)
- N-(3-Chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide (CAS 836640-15-4)
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- N-(4-Chlorophenyl)-N-methyl-1-oxo-2-[(pyridin-2-yl)methyl]-1,2-dihydroisoquinoline-4-carboxamide (CAS 303995-37-1)
- 2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,4-dimethoxyphenyl)acetamide (CAS 851078-93-8)
- 2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,5-dimethoxyphenyl)acetamide (CAS 851079-13-5)
- 2-((1-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,4-dimethoxyphenyl)acetamide (CAS 688337-20-4)
Recommended Standards
- N'-((1H-Indol-3-yl)methylene)-2-((4-chlorobenzyl)oxy)benzohydrazide (CAS 348584-76-9)
- N'-((1H-Indol-3-yl)methylene)-4-((4-chlorobenzyl)oxy)benzohydrazide (CAS 339201-57-9)
- 2-(3-chloropropyl)-3-(3,4-dimethoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid (CAS 1011412-52-4)
- N-(2-Benzylphenyl)-2-(7-chloro-4-oxoquinazolin-3(4H)-yl)acetamide (CAS 853319-00-3)
- 1-(1,2,3,4-Tetrahydronaphthalen-1-yl)-1h-pyrazol-5-amine hydrochloride (CAS 1208634-84-7)
- (S)-1-(3-Methoxyphenyl)propan-1-amine (CAS 623143-35-1)
- 2-(4-Fluorophenoxy)-3-nitropyridine (CAS 147143-58-6)
- 1-Ethoxy-2-methyl-1-penten-3-one (CAS 187222-11-3)
- 4-(Pyridin-3-ylmethanesulfonyl)benzoic acid (CAS 1016722-46-5)
- 2-Chloro-5-[[(4-methoxyphenyl)-2-propen-1-ylamino]sulfonyl]benzoic acid (CAS 438030-75-2)
- Pentafluorophenyldiphenylphosphate (CAS 138687-69-1)
- 2,2-Dimethyl-2,4-dihydro-1,3-benzodioxine-6-carbaldehyde (CAS 54030-33-0)
- 4-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-3,5-difluorobenzaldehyde (CAS 586382-05-0)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com