(E)-5-(2-((2,4-difluorophenyl)amino)vinyl)-3-phenylisoxazole-4-carbonitrile CAS 303995-81-5
| CAS No. | 303995-81-5 |
| Molecular Formula | C18H11F2N3O |
| Molecular Weight | 323.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (E)-5-(2-((2,4-difluorophenyl)amino)vinyl)-3-phenylisoxazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(E)-5-(2-((2,4-difluorophenyl)amino)vinyl)-3-phenylisoxazole-4-carbonitrile (CAS 303995-81-5), molecular formula C18H11F2N3O and molecular weight 323.30 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (E)-5-(2-((2,4-difluorophenyl)amino)vinyl)-3-phenylisoxazole-4-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 323.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H11F2N3O |
| Molecular Weight | 323.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related E Standards
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Recommended Standards
- (6-(6-Amino-9H-purin-9-yl)-2-ethoxytetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol (CAS 175203-92-6)
- 1-((4-Methyl-2,6-dinitrophenyl)amino)cyclohexane-1-carboxylic acid (CAS 866155-55-7)
- (5-([1,3]Dioxolo[4,5-f]isoquinolin-8-yl)benzo[d][1,3]dioxol-4-yl)methanol (CAS 164991-68-8)
- 1-(4-Aminophenyl)-5-(2h-1,3-benzodioxol-5-yl)-1h-pyrazole-3-carboxylic acid (CAS 957505-46-3)
- 2-Amino-6-(trifluoromethyl)-1H-indole-3-carbonitrile (CAS 1242140-69-7)
- 3,5-Difluoro-2-nitrobenzonitrile (CAS 868596-13-8)
- 4-(Dimethylamino)benzo[b]thiophene-2-carboxylic acid hydrochloride (CAS 2137696-74-1)
- 5-(4-Methoxyphenyl)-3-(methylthio)-1,2,4-triazine (CAS 69466-83-7)
- tert-Butyl 3-{[2-(1h-indol-3-yl)ethyl]amino}propanoate (CAS 127209-02-3)
- 5-Amino-2-((2-methoxyphenoxy)methyl)benzoic acid (CAS 1344691-67-3)
- 3-Allyl-4-hydroxybenzonitrile (CAS 90923-69-6)
- 5-((2-(3-Bromophenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine (CAS 735323-91-8)
- 2-(3-Aminooxetan-3-yl)ethan-1-ol oxalate (CAS 1404373-81-4)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
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