N-(2,6-Difluorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine CAS 849199-78-6

Purity 97%+In StockPharmaceutical Standards
CAS No.849199-78-6
Molecular FormulaC18H12F2N4
Molecular Weight322.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2,6-Difluorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine CAS 849199-78-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 322.31 g/mol gives N-(2,6-Difluorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(2,6-Difluorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine (CAS 849199-78-6) is a high-purity analytical reference standard with the molecular formula C18H12F2N4 and a molecular weight of 322.31 g/mol.

N-(2,6-Difluorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine (C18H12F2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H12F2N4
Molecular Weight322.31 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms4

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