Methyl 5-(2-methoxy-2-oxoethyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate CAS 303995-96-2
| CAS No. | 303995-96-2 |
| Molecular Formula | C14H12F3N3O4 |
| Molecular Weight | 343.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 343.26 g/mol gives Methyl 5-(2-methoxy-2-oxoethyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 5-(2-methoxy-2-oxoethyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 303995-96-2), a certified reference material (molecular formula C14H12F3N3O4, MW 343.26 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 5-(2-methoxy-2-oxoethyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate (C14H12F3N3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12F3N3O4 |
| Molecular Weight | 343.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
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