Morpholine Impurity 5 CAS CATO-C4X-31685
| CAS No. | CATO-C4X-31685 |
| Molecular Formula | C14H15F6NO2 |
| Molecular Weight | 343.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Morpholine Impurity 5 (C14H15F6NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Morpholine Impurity 5 (CAS CATO-C4X-31685), a pharmacopoeial impurity reference standard (molecular formula C14H15F6NO2, MW 343.26 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Morpholine Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15F6NO2 |
| Molecular Weight | 343.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Morpholine Standards
- 4-(Morpholine-4-sulfonyl)-N*1*-(tetrahydro-furan-2-ylmethyl)-benzene-1,2-diamine (CAS 560998-12-1)
- 7-(Morpholine-4-sulfonyl)-3-(propan-2-yl)-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 1007999-27-0)
- 4-Methyl-2-(3-(morpholine-4-carbonyl)phenyl)isothiazolidin-3-one 1,1-dioxide (CAS 919629-33-7)
- 2-(5-Methyl-3-(morpholine-4-carbonyl)-1H-pyrazol-1-yl)-N,N-dipropylacetamide (CAS 1169958-71-7)
- 1-ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole-2-thiol (CAS 733030-44-9)
- (4-{[(Morpholine-4-carbonyl)-amino]-methyl}-phenyl)-carbamic acid tert-butyl ester (CAS 1858240-82-0)
- 5-(Morpholine-4-sulfonyl)-2-phenoxyaniline (CAS 736948-90-6)
- 2-(Morpholine-4-carbonyl)-3-(5-(3-nitrophenyl)furan-2-yl)acrylonitrile (CAS 300700-39-4)
Recommended Standards
- Methyl 5-(2-methoxy-2-oxoethyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 303995-96-2)
- (6-(Pentylthio)-9H-purin-9-yl)methanol (CAS 14133-09-6)
- Methyl 5-(2-methoxy-2-oxoethyl)-1-(3-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 303995-97-3)
- 1,2,3,4-Tetrafluoro-7-phenoxyacridine (CAS 643032-47-7)
- Policresulen Impurity 8 (CAS CATO-C4X-19808)
- Ertugliflozin impurity 38 (CAS CATO-C4X-301138)
- Sulbactam Impurity 17 (CAS 24138-28-1)
- 5-(1,3-Dioxolan-2-yl)furan-2-carbaldehyde (CAS 117953-13-6)
- 2-Phenyl-1-((trimethylsilyl)ethynyl)-1,2,3,4-tetrahydroisoquinoline (CAS 823814-03-5)
- 8-Methylimidazo[1,2-c]pyrimidine (CAS 1353101-21-9)
- 4-(Ethylamino)butane-1-sulfonic acid (CAS 89585-27-3)
- Trimetazidine Impurity 18 (CAS CATO-C4X-180318)
- 3-(Benzo[d]thiazol-2-yl)-1,2,4-oxadiazole (CAS 39512-78-2)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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