3-Chloro-N-hydroxy-5-(trifluoromethyl)picolinimidamide CAS 303997-55-9
| CAS No. | 303997-55-9 |
| Molecular Formula | C7H5ClF3N3O |
| Molecular Weight | 239.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-N-hydroxy-5-(trifluoromethyl)picolinimidamide (CAS 303997-55-9) is a high-purity analytical reference standard with the molecular formula C7H5ClF3N3O and a molecular weight of 239.58 g/mol.
3-Chloro-N-hydroxy-5-(trifluoromethyl)picolinimidamide (C7H5ClF3N3O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-N-hydroxy-5-(trifluoromethyl)picolinimidamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF3N3O |
| Molecular Weight | 239.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Methyl 4-chloro-2-(trifluoromethyl)nicotinate (CAS 1018678-40-4)
- 3-Chloro-5-(trifluoromethyl)picolinohydrazide (CAS 1033463-30-7)
- Methyl 3-chloro-2-(trifluoromethyl)isonicotinate (CAS 1034132-07-4)
- Methyl 2-Chloro-6-(trifluoromethyl)nicotinate (CAS 1073129-57-3)
- 5-Chloro-2-(trifluoromethoxy)benzamide (CAS 1092461-18-1)
- 6-Chloro-n-(2,2,2-trifluoroethyl)pyridazine-3-carboxamide (CAS 1178187-52-4)
- Methyl 6-chloro-5-(trifluoromethyl)picolinate (CAS 1211518-35-2)
- Methyl 4-chloro-6-(trifluoromethyl)nicotinate (CAS 1211539-36-4)
Recommended Standards
- 3-Chloro-5-(trifluoromethoxy)benzamide (CAS 886503-25-9)
- 4-Amino-3-chloro-5-(trifluoromethyl)benzoic acid (CAS 95656-52-3)
- 3-Chloro-4-(trifluoromethoxy)benzamide (CAS 40251-61-4)
- 4-Chloro-3-(trifluoromethoxy)benzamide (CAS 886500-81-8)
- (2S)-1-ethoxypropan-2-amine hydrochloride (CAS 1380094-35-8)
- 2-((5-Chloropyridin-3-yl)oxy)ethan-1-amine (CAS 497949-30-1)
- (R)-2-(2,2-diisopropyl-1,3-dioxolan-4-yl)ethan-1-ol (CAS 1820574-15-9)
- 4-Hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-3-carbonitrile (CAS 83544-53-0)
- 5-((3-(tert-Butyl)phenoxy)methyl)-1H-pyrazol-3(2H)-one (CAS 61190-95-2)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-{[4-(trifluoromethoxy)phenyl]amino}ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-01-7)
- N-Methyl-2-((6-((2-methylindolin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide (CAS 898457-04-0)
- 3-Amino-4,7-dihydroxy-2H-chromen-2-one hydrochloride (CAS 90322-50-2)
- 5-Nitro-2-(p-tolylthio)benzaldehyde (CAS 175278-42-9)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com