(4-(4-Chlorophenyl)piperazin-1-yl)(6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)methanone CAS 303997-59-3
| CAS No. | 303997-59-3 |
| Molecular Formula | C19H15ClF3N3OS |
| Molecular Weight | 425.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4-(4-Chlorophenyl)piperazin-1-yl)(6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)methanone is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (4-(4-Chlorophenyl)piperazin-1-yl)(6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)methanone (CAS 303997-59-3), a certified reference material (molecular formula C19H15ClF3N3OS, MW 425.86 g/mol) for analytical method development and quality control.
The molecular framework of (4-(4-Chlorophenyl)piperazin-1-yl)(6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)methanone (C19H15ClF3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (4-(4-Chlorophenyl)piperazin-1-yl)(6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15ClF3N3OS |
| Molecular Weight | 425.86 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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Recommended Standards
- 3-Amino-N-(4-chlorobenzyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626227-31-4)
- 3,4,5-Tribromo-1-(4-nitrophenyl)-1H-pyrazole (CAS 175135-29-2)
- N-(4-chlorobenzyl)-2-((3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)acetamide (CAS 626221-53-2)
- 2,4-Dimethyl 5-(3-chlorobenzamido)-3-(2-methoxy-2-oxoethyl)thiophene-2,4-dicarboxylate (CAS 338393-17-2)
- N-((6-Methyl-4-oxo-1,4-dihydropyrimidin-2-yl)methyl)acetamide (CAS 79898-99-0)
- (4-(Pyrimidin-5-yl)phenyl)methanol (CAS 198084-13-8)
- Methyl 5-cyano-1-(4-fluorophenyl)-4-methyl-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 339018-13-2)
- 7-Chloro-5-(2-chlorophenyl)-1-methyl-[1,2,4]triazolo[4,3-a]quinoline (CAS 54196-60-0)
- (+/-)-Anatoxin A fumarate (CAS 1219922-30-1)
- 1031582-05-4 [3-Oxo-6-(piperidin-1-ylcarbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetic acid MFCD14281735 (CAS 1031582-05-4)
- (S)-3-(Pyrrolidin-2-yl)aniline hydrochloride (CAS 2061996-76-5)
- n-(2-Ethoxyethyl)-3,3-dimethylcyclohexan-1-amine (CAS 1340075-63-9)
- Etomidate Impurity 30 (CAS CATO-C4X-188430)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
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