N-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]-4-methoxyaniline CAS 303997-70-8
| CAS No. | 303997-70-8 |
| Molecular Formula | C15H12ClF3N2O |
| Molecular Weight | 328.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]-4-methoxyaniline (CAS 303997-70-8), a certified reference material (molecular formula C15H12ClF3N2O, MW 328.72 g/mol) for analytical method development and quality control.
The molecular framework of N-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]-4-methoxyaniline (C15H12ClF3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]-4-methoxyaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12ClF3N2O |
| Molecular Weight | 328.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-(5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1-(4-chlorophenyl)prop-2-en-1-one (CAS 648859-49-8)
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- 2-chloro-N-(2,6-dimethylphenyl)-4-(trifluoromethyl)nicotinamide (CAS 680213-81-4)
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- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com