2-chloro-N-(2,6-dimethylphenyl)-4-(trifluoromethyl)nicotinamide CAS 680213-81-4
| CAS No. | 680213-81-4 |
| Molecular Formula | C15H12ClF3N2O |
| Molecular Weight | 328.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-chloro-N-(2,6-dimethylphenyl)-4-(trifluoromethyl)nicotinamide (CAS 680213-81-4), a certified reference material (molecular formula C15H12ClF3N2O, MW 328.72 g/mol) for analytical method development and quality control.
2-chloro-N-(2,6-dimethylphenyl)-4-(trifluoromethyl)nicotinamide (C15H12ClF3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12ClF3N2O |
| Molecular Weight | 328.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(m-tolyl)acetamide (CAS 302842-66-6)
- 3-(5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1-(4-chlorophenyl)prop-2-en-1-one (CAS 648859-49-8)
- 6-Chloro-N-(4-(methylsulfonyl)phenyl)-5-nitropyrimidin-4-amine (CAS 733751-06-9)
- Methyl 3-((2-chloro-5-nitropyrimidin-4-yl)amino)-4-methylthiophene-2-carboxylate (CAS 2622273-34-9)
- N-(4-chloro-3-nitrophenyl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide (CAS 329779-13-7)
- 2-(((2-Chloro-5-nitrophenyl)imino)methyl)-3-hydroxy-1H-inden-1-one (CAS 1023532-89-9)
- 2-[(7-Chloro-4-nitro-2,1,3-benzoxadiazol-5-yl)amino]ethyl butyrate (CAS 697262-42-3)
- 1-((2-Chloro-5-(trifluoromethyl)phenyl)sulfonyl)piperazine (CAS 731776-55-9)
Recommended Standards
- 2-(4-Chlorobenzoyl)-N,N-dimethyl-5-(trifluoromethyl)pyridin-3-amine (CAS 306977-47-9)
- N-[(E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]-4-methoxyaniline (CAS 303997-70-8)
- 1-(2-Chlorobenzyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 897540-69-1)
- 6-(Benzyloxy)-4-nitropyridine-2-sulfonyl chloride (CAS 1393547-72-2)
- (R)-2-Benzyl-4-(tert-butoxy)-4-oxobutyric Acid (CAS 122225-33-6)
- Methyl 3-amino-3-(pyridin-4-yl)butanoate (CAS 1541050-78-5)
- (R)-4-(tert-butoxycarbonyl)-2,2-dimethylmorpholine-3-carboxylic acid (CAS 1416444-90-0)
- 4-Amino-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylic acid (CAS 1429418-72-3)
- 2-Bromospiro[9H-fluorene-9,9'-[9H]xanthene] (CAS 899422-06-1)
- 1-[(4-Bromo-2-chlorophenyl)carbonyl]pyrrolidine (CAS 877383-54-5)
- N-(1-(2-Aminoacetyl)pyrrolidin-3-yl)-N-methylacetamide (CAS 1353976-98-3)
- Ethyl 2,4-dibromo-3-fluorobenzoate (CAS 1804932-59-9)
- Methyl 7-hydroxybenzo[b]thiophene-6-carboxylate (CAS 1000773-57-8)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
Why CATO?
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