4-(4-chlorophenyl)-3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2(5H)-furanone CAS 303997-73-1
| CAS No. | 303997-73-1 |
| Molecular Formula | C16H8Cl2F3NO2 |
| Molecular Weight | 374.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(4-chlorophenyl)-3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2(5H)-furanone (CAS 303997-73-1), a certified reference material (molecular formula C16H8Cl2F3NO2, MW 374.14 g/mol) for analytical method development and quality control.
4-(4-chlorophenyl)-3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2(5H)-furanone (C16H8Cl2F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2F3NO2 |
| Molecular Weight | 374.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chlorophenyl Standards
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- 4-Chlorophenyl N-(4-chlorophenyl)-N-(methylsulfonyl)glycinate (CAS 866131-09-1)
- (2E)-3-(4-Chlorophenyl)-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one (CAS 95793-51-4)
- 1-(3-((4-Chlorophenyl)sulfonyl)azetidin-1-yl)-2-(cyclopentylthio)ethan-1-one (CAS 1448073-78-6)
- (5E)-3-(4-Chlorophenyl)-5-{[4-(propan-2-yl)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 882082-92-0)
- 2-[2-(4-chlorophenyl)adamantan-2-yl]-1-(morpholin-4-yl)ethan-1-one 400085-09-8 6F-939 (CAS 400085-09-8)
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Recommended Standards
- 2-(2-Chloro-4-(trifluoromethyl)phenyl)-5-(2-chlorophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000575-12-1)
- 2-Bromo-4-methoxy-6-[(1E)-{[4-(trifluoromethyl)phenyl]imino}methyl]phenol (CAS 477848-17-2)
- cis-Dichloro(2-aminomethylpyridine)platinum(II) (CAS 64174-32-9)
- 4-(Dimethoxymethyl)-2-(3-fluoro-4-iodophenyl)pyrimidine (CAS 477870-93-2)
- 1-(Cyclopentylmethyl)cyclopropan-1-amine (CAS 1526868-92-7)
- 5-Bromo-4-fluoro-3-methylbenzo[d]oxazol-2(3H)-one (CAS 2387594-61-6)
- 2-((4-Chloro-N-(2,4-dichloro-5-methoxyphenyl)phenyl)sulfonamido)-N-(2,4-difluorophenyl)acetamide (CAS 338961-81-2)
- 3-(5-sulfanyl-1H-1,2,3,4-tetrazol-1-yl)propanoic acid (CAS 61197-34-0)
- N-Benzyl-N-butylpyrrolidin-3-amine (CAS 820984-49-4)
- 4-(3-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2(1H)-one (CAS 1225573-88-5)
- 2,6-Dimethyl-4-[(oxiran-2-yl)methyl]morpholine (CAS 90950-33-7)
- (R)-2-Isopropylsuccinic acid (CAS 1187-69-5)
- 2-Chloro-5,6-dihydrobenzo[H]quinazoline (CAS 13036-53-8)
- Semaglutide impurity 103 (CAS 1446013-07-5)
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