6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-thiol CAS 304684-43-3
| CAS No. | 304684-43-3 |
| Molecular Formula | C7H4F3N3S |
| Molecular Weight | 219.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-thiol (C7H4F3N3S) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-thiol (CAS 304684-43-3), a certified reference material (molecular formula C7H4F3N3S, MW 219.19 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F3N3S |
| Molecular Weight | 219.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 5-(Trifluoromethyl)thiazolo[4,5-b]pyridin-2-amine (CAS 1206250-51-2)
- 6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine (CAS 1206250-52-3)
- 6-(Trifluoromethyl)thiazolo[4,5-c]pyridin-2-amine (CAS 1266118-94-8)
- 7-(Trifluoromethyl)thiazolo[4,5-b]pyridin-2-amine (CAS 1934829-14-7)
- 4-(Trifluoromethyl)benzo[d]thiazol-2(3H)-one, 97% (CAS 100831-20-7)
- 2-((4-(Trifluoromethyl)benzyl)oxy)ethanamine (CAS 1249911-92-9)
- 2-(Trifluoromethyl)benzo[d]thiazol-7-ol (CAS 1261545-10-1)
- 2-(Trifluoromethyl)benzo[d]thiazol-6-ol (CAS 1261740-05-9)
Recommended Standards
- 6-(Methoxycarbonyl)-1h-indole-3-carboxylic acid (CAS 773869-62-8)
- 6,7,8-Trihydroxy-1-(hydroxymethyl)-2-oxa-4-azabicyclo[3.3.1]Nonan-3-one (CAS 85281-06-7)
- 6-(3,5-Difluorophenyl)nicotinaldehyde (CAS 898404-56-3)
- 6-Methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (CAS 848824-88-4)
- 1-(2-(Benzylthio)-4,5-dihydro-1H-imidazol-1-yl)-2-phenylethan-1-one (CAS 851864-32-9)
- 1-Ethyl-2-fluoro-3-methyl-2,3-dihydro-1H-imidazole (CAS 518361-20-1)
- tert-Butyl [3,3'-bipyridine]-6-carboxylate (CAS 1403333-26-5)
- (2RS,3RS)-1-Chloroacetylamino-3-(2-ethoxy-d5-phenoxy)-2-hydroxy-3-phenylpropane (CAS 1184995-73-0)
- 1,1,1-Trifluoro-N-[(11bS)-4-oxido-2,6-di-9-phenanthrenyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide (CAS 1256334-83-4)
- 3-(3-bicyclo[4.2.0]octa-1,3,5-trienyl)propanoyl chloride (CAS 2271393-81-6)
- n-Tetradecane-d30 (CAS 204244-81-5)
- 3-(2-{[(2,4-dichlorophenyl)methyl]sulfanyl}pyrimidin-4-yl)-1-(4-methylphenyl)-1,4-dihydropyridazin-4-one (CAS 478077-67-7)
- (6-Nitrobenzo[d]isoxazol-3-yl)methanol (CAS 102741-52-6)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
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